LAEL147_000281800

DNA-directed RNA polymerases I and III subunit RPAC1, putative
Leishmania aethiopica L147 OG6: OG6_102180 OG7: OG7_0003550 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000560500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000614300 ⚠
RNA polymerase ii largest subunit
— +2 more Both
LAEL147_000504100 ⚠
DNA-directed RNA polymerase-like protein
— Both
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— Both
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— Both
LAEL147_000014400 ⚠
RNA polymerase ii largest subunit
— +2 more Both
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— +2 more Both
LAEL147_000237600 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more Both
LAEL147_000406100 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LAEL147_000470700 ⚠
DNA-directed RNA polymerase II-like protein
— OG7
LAEL147_000057000 ⚠
hypothetical protein, conserved
— Both
LAEL147_000140200 ⚠
Core histone H2A/H2B/H3/H4, putative
— Both
LAEL147_000141700 ⚠
histone H3, putative
— Both
LAEL147_000384400 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
LAEL147_000618400 ⚠
acetyl-CoA carboxylase, putative
— Both
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— Both
LAEL147_000688600 ⚠
mitogen-activated protein kinase, putative
— Both
LAEL147_000692100 ⚠
hypothetical protein
— OG6
LAEL147_000832600 ⚠
Spc97 / Spc98 family, putative
— Both
LAEL147_000738100 ⚠
Zinc finger domain containing protein, putati
— Both
LAEL147_000745600 ⚠
GRIP domain containing protein, putative
— Both
LAEL147_000676900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000871100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000558400 ⚠
WW domain containing protein, putative
— Both
LAEL147_000326700 ⚠
adenylate kinase, putative
— Both
LAEL147_000357500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000558500 ⚠
hypothetical protein
— Both
LAEL147_000772700 ⚠
hypothetical protein, conserved
— Both
LAEL147_000137300 ⚠
Chromatin assembly factor 1 subunit A, putati
— Both
LAEL147_000149700 ⚠
hypothetical protein, conserved
— Both
LAEL147_000182900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000265800 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— Both
LAEL147_000131800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000265700 ⚠
DNA-directed RNA polymerase II/III subunit, p
— Both
LAEL147_000854700 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LAEL147_000244300 ⚠
histone H2A, putative
— Both
LAEL147_000105300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000083000 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000334100 ⚠
histone deacetylase, putative
— Both
LAEL147_000110700 ⚠
histone deacetylase, putative
— Both
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— Both
LAEL147_000164100 ⚠
ubiquitin hydrolase, putative
— Both
LAEL147_000177000 ⚠
ATP-dependent RNA helicase, putative
— Both
LAEL147_000251900 ⚠
ATP-dependent RNA helicase, putative
— Both
LAEL147_000101000 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LAEL147_000266100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000106200 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LAEL147_000489900 ⚠
RNA polymerase B subunit RPB8, putative
— OG7
LAEL147_000279400 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.