LAEL147_000292700

DNA-directed RNA polymerase polypeptide, putative
Leishmania aethiopica L147 OG6: OG6_100190 OG7: OG7_0001821 178 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 178 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000504100 ⚠
DNA-directed RNA polymerase-like protein
— +1 more Both
LAEL147_000515800 ⚠
DNA-directed RNA polymerase I-like protein
— Both
LAEL147_000047600 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LAEL147_000371100 ⚠
Csl4p homologue, putative
— OG7
LAEL147_000281800 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
LAEL147_000614300 ⚠
RNA polymerase ii largest subunit
— +4 more Both
LAEL147_000692100 ⚠
hypothetical protein
— OG6
LAEL147_000014400 ⚠
RNA polymerase ii largest subunit
— +4 more Both
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— +4 more Both
LAEL147_000614600 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LAEL147_000614700 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LAEL147_000470700 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LAEL147_000237600 ⚠
DNA-directed rna polymerase I largest subunit
— +1 more OG7
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LAEL147_000686900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— OG7
LAEL147_000414400 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LAEL147_000533900 ⚠
histone H2A, putative
— OG7
LAEL147_000434600 ⚠
heat shock 70 protein-like protein
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000696400 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000826100 ⚠
neurobeachin/beige protein, putative
— OG7
LAEL147_000349700 ⚠
CCR4 associated factor, putative
— OG7
LAEL147_000006200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000139500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000228400 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000301600 ⚠
tubulin-tyrosine ligase, putative
— OG7
LAEL147_000480700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000517200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAEL147_000570600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000801500 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000653100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000854700 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
LAEL147_000711800 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG7
LAEL147_000822800 ⚠
translation elongation factor 1-beta, putativ
— OG7
LAEL147_000711600 ⚠
elongation factor 1-beta
— OG7
LAEL147_000711900 ⚠
elongation factor 1-beta
— OG7
LAEL147_000031100 ⚠
ribosomal RNA processing protein, putative
— OG7
LAEL147_000279400 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LAEL147_000862700 ⚠
exosome-associated protein 4, putative
— OG7
LAEL147_000842000 ⚠
exosome complex exonuclease RRP41, putative
— OG7
LAEL147_000511500 ⚠
Hsp70 protein, putative
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000349300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000214900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000091300 ⚠
RAVE protein 1 C terminal, putative
— OG7
LAEL147_000349200 ⚠
exosome complex exonuclease RRP45 homolog, pu
— OG7
LAEL147_000106200 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LAEL147_000659300 ⚠
exosome-associated protein 2, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.