LAEL147_000047600

exosome complex exonuclease RRP40, putative
Leishmania aethiopica L147 OG6: OG6_102463 OG7: OG7_0007513 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000031100 ⚠
ribosomal RNA processing protein, putative
— Both
LAEL147_000842000 ⚠
exosome complex exonuclease RRP41, putative
— Both
LAEL147_000862700 ⚠
exosome-associated protein 4, putative
— OG7
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000371100
Csl4p homologue, putative
— Both
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000307700
RNasePH-like protein
— Both
LAEL147_000406100 ⚠
RNA polymerase I second largest subunit, puta
— Both
LAEL147_000349200 ⚠
exosome complex exonuclease RRP45 homolog, pu
— +2 more Both
LAEL147_000659300 ⚠
exosome-associated protein 2, putative
— +2 more Both
LAEL147_000189700 ⚠
exosome complex exonuclease, putative
— Both
LAEL147_000190100 ⚠
exosome complex exonuclease, putative
— Both
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000413100
hypothetical protein, conserved
— Both
LAEL147_000414400 ⚠
Conserved hypothetical ATP binding protein, p
— Both
LAEL147_000039300
protein kinase, putative
— Both
LAEL147_000711800 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAEL147_000822800 ⚠
translation elongation factor 1-beta, putativ
— Both
LAEL147_000711600 ⚠
elongation factor 1-beta
— Both
LAEL147_000711900 ⚠
elongation factor 1-beta
— Both
LAEL147_000430400 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000842500 ⚠
cullin-like protein
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
LAEL147_000607700 ⚠
polyubiquitin, putative
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000614300 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000583200 ⚠
protein mkt1, putative
— OG7
LAEL147_000279400 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000150000 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LAEL147_000430500 ⚠
DNA polymerase sigma-like protein
— OG7
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LAEL147_000653400 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LAEL147_000051300 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LAEL147_000813900 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LAEL147_000482500 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
LAEL147_000786500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LAEL147_000062700 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LAEL147_000236400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAEL147_000695500 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LAEL147_000507600 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LAEL147_000369300 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000063400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LAEL147_000868200 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000157100 ⚠
adaptin-related protein-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.