LAEL147_000189700

exosome complex exonuclease, putative
Leishmania aethiopica L147 OG6: OG6_101400 OG7: OG7_0006776 45 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 45 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000349200 ⚠
exosome complex exonuclease RRP45 homolog, pu
— +4 more Both
LAEL147_000659300 ⚠
exosome-associated protein 2, putative
— +4 more Both
LAEL147_000047600 ⚠
exosome complex exonuclease RRP40, putative
— Both
LAEL147_000842000 ⚠
exosome complex exonuclease RRP41, putative
— Both
LAEL147_000031100 ⚠
ribosomal RNA processing protein, putative
— Both
LAEL147_000862700 ⚠
exosome-associated protein 4, putative
— OG7
LAEL147_000271700 ⚠
heat shock protein 110, putative
— OG7
LAEL147_000437100 ⚠
mitochondrial RNA binding complex 1 subunit,
— Both
LAEL147_000711800 ⚠
EF-1 guanine nucleotide exchange domain conta
— Both
LAEL147_000822800 ⚠
translation elongation factor 1-beta, putativ
— Both
LAEL147_000711600 ⚠
elongation factor 1-beta
— Both
LAEL147_000711900 ⚠
elongation factor 1-beta
— Both
LAEL147_000734200 ⚠
exosome subunit rrp6p homologue, putative
— Both
LAEL147_000194700 ⚠
mRNA capping enzyme, beta chain, putative
— Both
LAEL147_000371100 ⚠
Csl4p homologue, putative
— Both
LAEL147_000434600 ⚠
heat shock 70 protein-like protein
— OG7
LAEL147_000512000 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000025300 ⚠
HSP70-like protein
— OG7
LAEL147_000799400 ⚠
Hsp70 protein, putative
— OG7
LAEL147_000281800 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000430400 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LAEL147_000162000 ⚠
proteasome beta-1 subunit, putative
— OG7
LAEL147_000790300 ⚠
proteasome beta 2 subunit, putative
— OG7
LAEL147_000414400 ⚠
Conserved hypothetical ATP binding protein, p
— Both
LAEL147_000560500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000828200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000861600 ⚠
paraflagellar rod component, putative
— Both
LAEL147_000024400 ⚠
pre-mRNA processing factor 3 (PRP3)/Protein o
— Both
LAEL147_000716300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000101800 ⚠
adaptor complex protein (AP) 3 delta subunit
— Both
LAEL147_000515800 ⚠
DNA-directed RNA polymerase I-like protein
— Both
LAEL147_000406100 ⚠
RNA polymerase I second largest subunit, puta
— Both
LAEL147_000413100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000307700 ⚠
RNasePH-like protein
— Both
LAEL147_000388100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000463200 ⚠
parallel beta-helix repeat, putative
— Both
LAEL147_000825400 ⚠
proteasome beta 5 subunit, putative
— Both
LAEL147_000114100 ⚠
calmodulin-like protein containing EF hand do
— Both
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000407300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000511500 ⚠
Hsp70 protein, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.