LAEL147_000512000

heat-shock protein hsp70, putative
Leishmania aethiopica L147 OG6: OG6_100083 OG7: OG7_0000777 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— +1 more OG6
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— +1 more OG6
LAEL147_000573300 ⚠
heat-shock protein hsp70, putative
— +2 more OG6
LAEL147_000511500 ⚠
Hsp70 protein, putative
— +1 more OG6
LAEL147_000572500 ⚠
Hsp70 protein, putative
— +2 more OG6
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— +1 more OG6
LAEL147_000219300 ⚠
AhpC/TSA family/C-terminal domain of 1-Cys pe
— OG6
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000705700 ⚠
tRNA pseudouridine synthase, putative
— Both
LAEL147_000848300 ⚠
cysteine synthase
— OG6
LAEL147_000550000 ⚠
kinesin, putative
— OG6
LAEL147_000524000 ⚠
guanine deaminase, putative
— OG6
LAEL147_000560000 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAEL147_000044000 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LAEL147_000855700 ⚠
paraflagellar rod component, putative
— OG6
LAEL147_000740900 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— Both
LAEL147_000842900 ⚠
ATP synthase, putative
— Both
LAEL147_000761400 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000096100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LAEL147_000096500 ⚠
flavoprotein subunit-like protein
— Both
LAEL147_000050400 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LAEL147_000011700 ⚠
hypothetical protein, conserved
— Both
LAEL147_000331800 ⚠
protein kinase, putative
— Both
LAEL147_000038100 ⚠
fatty acyl CoA syntetase 1, putative
— OG6
LAEL147_000023800 ⚠
fatty acyl CoA syntetase 1, putative
— OG6
LAEL147_000023900 ⚠
fatty acyl CoA syntetase 1, putative
— OG6
LAEL147_000023600 ⚠
fatty acyl CoA syntetase 1, putative
— OG6
LAEL147_000024000 ⚠
fatty acyl CoA syntetase 1, putative
— OG6
LAEL147_000361400 ⚠
acetyl-CoA synthetase, putative
— OG6
LAEL147_000357000 ⚠
acetyl-CoA synthetase, putative
— OG6
LAEL147_000339900 ⚠
Uncharacterised protein family UPF0066, putat
— Both
LAEL147_000842000 ⚠
exosome complex exonuclease RRP41, putative
— OG6
LAEL147_000640800 ⚠
chaperonin HSP60, mitochondrial precursor
— OG6
LAEL147_000711800 ⚠
EF-1 guanine nucleotide exchange domain conta
— OG6
LAEL147_000829900 ⚠
TCP-1/cpn60 chaperonin family, putative
— OG6
LAEL147_000822800 ⚠
translation elongation factor 1-beta, putativ
— OG6
LAEL147_000829800 ⚠
chaperonin HSP60, mitochondrial precursor
— OG6
LAEL147_000711600 ⚠
elongation factor 1-beta
— OG6
LAEL147_000711900 ⚠
elongation factor 1-beta
— OG6
LAEL147_000474200 ⚠
trypanothione synthetase, putative
— OG6
LAEL147_000659300 ⚠
exosome-associated protein 2, putative
— OG6
LAEL147_000349200 ⚠
exosome complex exonuclease RRP45 homolog, pu
— OG6
LAEL147_000198800 ⚠
hypothetical protein
— OG6
LAEL147_000340500 ⚠
guide RNA associated protein, GAP2, putative
— Both
LAEL147_000517500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000855900 ⚠
protein kinase-like protein
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000812500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000685400 ⚠
dual-specificity protein kinase, putative
— OG7
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.