LAEL147_000096100

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Leishmania aethiopica L147 OG6: OG6_100250 OG7: OG7_0002306 159 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 159 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000780600 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAEL147_000670500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000855700 ⚠
paraflagellar rod component, putative
— Both
LAEL147_000807900 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LAEL147_000794500 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LAEL147_000373600 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LAEL147_000261800 ⚠
ATP12 chaperone protein, putative
— OG7
LAEL147_000554700 ⚠
Armadillo/beta-catenin-like repeats, putative
— OG7
LAEL147_000552200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000522500 ⚠
heat shock protein 90, putative
— OG7
LAEL147_000333100 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
LAEL147_000144300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000351600 ⚠
GDP-mannose pyrophosphorylase
— OG7
LAEL147_000468700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000209200 ⚠
serine/threonine-protein kinase, putative
— OG7
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LAEL147_000508800 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LAEL147_000717000 ⚠
inositol 5-phosphatase-like protein
— OG7
LAEL147_000133600 ⚠
Exonuclease, putative
— OG7
LAEL147_000768600 ⚠
protein kinase-like protein
— OG7
LAEL147_000517500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000743400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAEL147_000354000 ⚠
pteridine reductase 1
— OG7
LAEL147_000785100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000725800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000685400 ⚠
dual-specificity protein kinase, putative
— OG7
LAEL147_000812500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000692300 ⚠
heat shock protein, putative
— OG7
LAEL147_000668200 ⚠
heat shock protein 83-17
— OG7
LAEL147_000382000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LAEL147_000399400 ⚠
beta-galactofuranosyltransferase-like protein
— OG7
LAEL147_000652900 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000870000 ⚠
beta-adaptin protein, putative
— OG7
LAEL147_000551100 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LAEL147_000630400 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LAEL147_000745600 ⚠
GRIP domain containing protein, putative
— OG7
LAEL147_000060700 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LAEL147_000623000 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LAEL147_000774500 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000855900 ⚠
protein kinase-like protein
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000884500 ⚠
beta-adaptin, putative
— OG7
LAEL147_000445100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000358000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000429800 ⚠
pseudouridylate synthase-like protein
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000773700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000878700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000747600 ⚠
nucleolar protein family a, putative
— OG7
LAEL147_000842800 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.