LAEL147_000552200

hypothetical protein, conserved

Leishmania aethiopica L147 OG6: OG6_158251 OG7: OG7_0052285 207 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 207 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000694000 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	OG7
LAEL147_000026000 ⚠ ubiquitin activating enzyme, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010542 OG7 LdBPK_080230.1 ↔ LdBPK_300580.1	OG7
LAEL147_000322800 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	OG7
LAEL147_000285000 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_300580.1	Both
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	OG7
LAEL147_000105200 WD domain, G-beta repeat, putative	—	OG6 LdBPK_080420.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_300580.1	Both
LAEL147_000725600 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 LdBPK_300580.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	Both
LAEL147_000686600 Ribosome assembly protein rrb1, putative	—	OG6 LdBPK_300580.1 ↔ LdBPK_332020.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005619 OG7 LdBPK_300580.1 ↔ LdBPK_332020.1	Both
LAEL147_000396000 tubulin folding cofactor D, putative	—	OG6 LdBPK_242100.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003118 OG7 LdBPK_242100.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003118	Both
LAEL147_000164700 cysteinyl-tRNA synthetase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_006977 OG7 LdBPK_120255.1 ↔ LdBPK_300580.1	Both
LAEL147_000103200 ⚠ ubiquitin-activating enzyme-like protein	—	OG6 LdBPK_080230.1 ↔ LdBPK_300580.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010542 OG7 LdBPK_080230.1 ↔ LdBPK_300580.1	Both
LAEL147_000152900 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG6 LdBPK_110640.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	Both
LAEL147_000153000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG6 LdBPK_110640.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	Both
LAEL147_000277600 C-terminal motor kinesin, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_006065	OG6
LAEL147_000870000 ⚠ beta-adaptin protein, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_004597	OG7
LAEL147_000382000 ⚠ inositol polyphosphate phosphatase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007569	OG7
LAEL147_000692300 ⚠ heat shock protein, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009151	OG7
LAEL147_000743400 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003118	OG7
LAEL147_000652900 ⚠ ubiquitin hydrolase, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005374 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005374	Both
LAEL147_000717000 ⚠ inositol 5-phosphatase-like protein	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007569	OG7
LAEL147_000468700 hypothetical protein, conserved	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005512	OG7
LAEL147_000096100 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003118	OG7
LAEL147_000044000 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003118	OG7
LAEL147_000808700 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003118	OG7
LAEL147_000558500 ⚠ hypothetical protein	—	OG7 LdBPK_161180.1 ↔ LdBPK_300580.1 OG7 LdBPK_300580.1 ↔ LdBPK_300970.1	OG7
LAEL147_000558400 ⚠ WW domain containing protein, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_300580.1 OG7 LdBPK_300580.1 ↔ LdBPK_300970.1	OG7
LAEL147_000090000 ⚠ ubiquitin-protein ligase-like, putative	—	OG7 LdBPK_161180.1 ↔ LdBPK_300580.1 OG7 LdBPK_300580.1 ↔ LdBPK_300970.1	OG7
LAEL147_000783900 ⚠ replication factor C, subunit 3, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LAEL147_000460100 ⚠ replication factor C, subunit 4, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LAEL147_000246900 ⚠ ATPase family associated with various cellula	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LAEL147_000304600 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LAEL147_000574300 ⚠ replication factor C, subunit 2, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LAEL147_000883800 ⚠ replication factor C, subunit 5, putative	—	OG7 LdBPK_241010.1 ↔ LdBPK_300580.1	OG7
LAEL147_000451500 ⚠ hypothetical protein	—	OG7 LdBPK_291830.1 ↔ LdBPK_300580.1	OG7
LAEL147_000721300 Zeta toxin, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_010958 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_010958	Both
LAEL147_000623000 Histone chaperone Rttp106-like, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_006113 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_006113	Both
LAEL147_000884500 ⚠ beta-adaptin, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_004597 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_004597	Both
LAEL147_000060700 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_009880	Both
LAEL147_000445100 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003586 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003586	Both
LAEL147_000295600 ⚠ developmentally regulated phosphoprotein-like	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003118	Both
LAEL147_000756200 vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005104 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005104	Both
LAEL147_000855700 paraflagellar rod component, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_004736	OG6
LAEL147_000761400 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008502	Both
LAEL147_000834900 dipeptidyl-peptidase 8-like serine peptidase,	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007536 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_007536	Both
LAEL147_000096500 ⚠ flavoprotein subunit-like protein	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008502	Both
LAEL147_000050400 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_007342	OG6
LAEL147_000745000 ⚠ geranylgeranyltransferase, putative	—	OG7 LdBPK_261450.1 ↔ LdBPK_300580.1	OG7
LAEL147_000045300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003118 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003118	Both
LAEL147_000468000 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005374	OG7
LAEL147_000745600 GRIP domain containing protein, putative	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003707 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003707	Both

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