LAEL147_000808700

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative
Leishmania aethiopica L147 OG6: OG6_129420 OG7: OG7_0002306 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000670500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000780600 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LAEL147_000807900 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LAEL147_000878700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000445100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000295600 ⚠
developmentally regulated phosphoprotein-like
— OG7
LAEL147_000819600 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LAEL147_000794500 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LAEL147_000756200 ⚠
vacuolar ATP synthase subunit d, putative
— OG7
LAEL147_000468000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000866800 ⚠
adaptin, putative
— OG7
LAEL147_000103200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LAEL147_000132100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000164100 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000067700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000846600 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LAEL147_000842900 ⚠
ATP synthase, putative
— OG7
LAEL147_000761400 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LAEL147_000834900 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
LAEL147_000220100 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LAEL147_000157100 ⚠
adaptin-related protein-like protein
— OG7
LAEL147_000210600 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LAEL147_000096500 ⚠
flavoprotein subunit-like protein
— OG7
LAEL147_000164700 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LAEL147_000721300 ⚠
Zeta toxin, putative
— OG7
LAEL147_000011700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000508100 ⚠
vacuolar ATP synthase subunit b, putative
— OG7
LAEL147_000199500 ⚠
protein kinase, putative
— OG7
LAEL147_000105200 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000763700 ⚠
threonyl-tRNA synthetase, putative
— OG7
LAEL147_000842800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000424300 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LAEL147_000747600 ⚠
nucleolar protein family a, putative
— OG7
LAEL147_000331800 ⚠
protein kinase, putative
— OG7
LAEL147_000202300 ⚠
protein kinase, putative
— OG7
LAEL147_000050700 ⚠
adenylosuccinate lyase, putative
— OG7
LAEL147_000358000 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000049400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000491500 ⚠
oxidoreductase-like protein
— OG7
LAEL147_000635800 ⚠
G5-interacting protein, putative
— OG7
LAEL147_000175200 ⚠
Triglyceride lipase, putative
— OG7
LAEL147_000698900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000073400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000855700 ⚠
paraflagellar rod component, putative
— OG7
LAEL147_000060400 ⚠
Leucine Rich repeat, putative
— OG7
LAEL147_000698700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000580800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000730400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000600600 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.