LAEL147_000761400

NADH-dependent fumarate reductase, putative
Leishmania aethiopica L147 OG6: OG6_104311 OG7: OG7_0003099 170 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 170 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000152900 ⚠
aminopeptidase, putative
— +2 more Both
LAEL147_000153000 ⚠
aminopeptidase, putative
— +2 more Both
LAEL147_000554700 ⚠
Armadillo/beta-catenin-like repeats, putative
— +2 more Both
LAEL147_000508100 ⚠
vacuolar ATP synthase subunit b, putative
— +2 more Both
LAEL147_000694000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000717000 ⚠
inositol 5-phosphatase-like protein
— OG7
LAEL147_000512000 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000511500 ⚠
Hsp70 protein, putative
— OG6
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000264600 ⚠
PA26 p53-induced protein (sestrin), putative
— Both
LAEL147_000339900 ⚠
Uncharacterised protein family UPF0066, putat
— Both
LAEL147_000518200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000210500 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LAEL147_000210600 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
LAEL147_000024900 ⚠
DNA-damage inducible protein DDI1-like protei
— +2 more Both
LAEL147_000394700 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LAEL147_000749600 ⚠
pyruvate kinase
— Both
LAEL147_000749500 ⚠
pyruvate kinase
— Both
LAEL147_000076200 ⚠
glutamine synthetase, putative
— Both
LAEL147_000189400 ⚠
pyrroline-5-carboxylate reductase
— Both
LAEL147_000277200 ⚠
polyprenyl synthase, putative
— Both
LAEL147_000341300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000560000 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— +2 more Both
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— +2 more Both
LAEL147_000333500 ⚠
60S ribosomal protein L37a, putative
— Both
LAEL147_000828300 ⚠
60S ribosomal protein L37a, putative
— Both
LAEL147_000358000 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LAEL147_000878700 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LAEL147_000520800 ⚠
NF-X1 type zinc finger containing protein, pu
— Both
LAEL147_000340500 ⚠
guide RNA associated protein, GAP2, putative
— Both
LAEL147_000144300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000445100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000181500 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LAEL147_000552200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000396000 ⚠
tubulin folding cofactor D, putative
— +2 more Both
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— Both
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— Both
LAEL147_000165200 ⚠
ornithine decarboxylase, putative
— Both
LAEL147_000756200 ⚠
vacuolar ATP synthase subunit d, putative
— Both
LAEL147_000855700 ⚠
paraflagellar rod component, putative
— OG6
LAEL147_000517500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000812500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000067700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000644100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000325300 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAEL147_000656100 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000855900 ⚠
protein kinase-like protein
— OG7
LAEL147_000199500 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.