LAEL147_000340500

guide RNA associated protein, GAP2, putative
Leishmania aethiopica L147 OG6: OG6_139815 OG7: OG7_0037740 152 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 152 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000011700
hypothetical protein, conserved
— Both
LAEL147_000686600
Ribosome assembly protein rrb1, putative
— Both
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000270500 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000270400 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— Both
LAEL147_000271200
hypothetical protein, conserved
— Both
LAEL147_000423300
hypothetical protein, conserved
— Both
LAEL147_000144200 ⚠
Zn-finger in Ran binding protein and others,
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— Both
LAEL147_000514600
transcription factor-like protein
— Both
LAEL147_000757700 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000581300 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LAEL147_000327700
ATP synthase, putative
— Both
LAEL147_000868500
branch point binding protein, putative
— Both
LAEL147_000512000 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000705700 ⚠
tRNA pseudouridine synthase, putative
— Both
LAEL147_000511500 ⚠
Hsp70 protein, putative
— OG6
LAEL147_000550000
kinesin, putative
— OG6
LAEL147_000560000
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAEL147_000044000 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LAEL147_000855700
paraflagellar rod component, putative
— OG6
LAEL147_000740900
vacuolar ATP synthase catalytic subunit A, pu
— Both
LAEL147_000842900
ATP synthase, putative
— Both
LAEL147_000761400 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000096100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LAEL147_000096500 ⚠
flavoprotein subunit-like protein
— Both
LAEL147_000050400 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LAEL147_000508100
vacuolar ATP synthase subunit b, putative
— Both
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000331800 ⚠
protein kinase, putative
— Both
LAEL147_000434100 ⚠
RNA-editing complex protein MP100, putative
— OG7
LAEL147_000538600 ⚠
Domain of unknown function (DUF4379), putativ
— OG7
LAEL147_000303200 ⚠
conserved protein, unknown function
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000774900 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000883800 ⚠
replication factor C, subunit 5, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000418000 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000559800 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LAEL147_000600600
hypothetical protein, conserved
— OG7
LAEL147_000807900 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LAEL147_000562700 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LAEL147_000067700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000132100
hypothetical protein, conserved
— OG7
LAEL147_000855900 ⚠
protein kinase-like protein
— OG7
LAEL147_000812500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000199500 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.