LAEL147_000857100

ubiquitin protein ligase, putative
Leishmania aethiopica L147 OG6: OG6_478893 OG7: OG7_0002947 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000686600 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LAEL147_000354400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000609000 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
LAEL147_000285100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000464500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000228500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000426000 ⚠
Lsm7p protein, putative
— OG7
LAEL147_000432900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000243900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000418000 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000103200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LAEL147_000559800 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LAEL147_000796900 ⚠
sm-f snRNP core complex protein, putative
— OG7
LAEL147_000005500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000632600 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LAEL147_000020500 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000853800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000150200 ⚠
chromatin binding protein, putative
— OG7
LAEL147_000721600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000433000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000748400 ⚠
sjogren s syndrome nuclear autoantigen 1, put
— OG7
LAEL147_000221000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000745300 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000501200 ⚠
replication factor A, 51kDa subunit, putative
— OG7
LAEL147_000503500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000065500 ⚠
Surp module, putative
— OG7
LAEL147_000340500 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LAEL147_000218900 ⚠
glutamate dehydrogenase
— OG7
LAEL147_000730300 ⚠
methyltransferase-like protein
— OG7
LAEL147_000322200 ⚠
HEAT-like repeat, putative
— OG7
LAEL147_000011700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000264600 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LAEL147_000156100 ⚠
PUB domain containing protein, putative
— OG7
LAEL147_000087600 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LAEL147_000494900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000863000 ⚠
Calponin homology (CH) domain containing prot
— OG7
LAEL147_000783400 ⚠
RNA-binding protein, putative
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000347900 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAEL147_000562700 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LAEL147_000429800 ⚠
pseudouridylate synthase-like protein
— OG7
LAEL147_000705700 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAEL147_000318800 ⚠
nucleotide-binding protein, putative
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000552200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000067300 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAEL147_000429900 ⚠
nucleotide binding protein-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.