LAEL147_000322200

HEAT-like repeat, putative
Leishmania aethiopica L147 OG6: OG6_158058 OG7: OG7_0008375 119 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 119 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000437500
hypothetical protein, conserved
— Both
LAEL147_000730400
hypothetical protein, conserved
— Both
LAEL147_000093300
hypothetical protein, conserved
— Both
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— Both
LAEL147_000270400 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— Both
LAEL147_000270500 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000156100
PUB domain containing protein, putative
— Both
LAEL147_000562700 ⚠
pseudouridine synthase A-like protein, putati
— Both
LAEL147_000155800
Leucine Rich repeat, putative
— Both
LAEL147_000031000
Soluble NSF attachment protein, SNAP, putativ
— Both
LAEL147_000285100
hypothetical protein, conserved
— Both
LAEL147_000105200
WD domain, G-beta repeat, putative
— Both
LAEL147_000268400
5-oxoprolinase, putative
— Both
LAEL147_000694000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000808700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LAEL147_000428700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000705700 ⚠
tRNA pseudouridine synthase, putative
— OG7
LAEL147_000429800 ⚠
pseudouridylate synthase-like protein
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000431000 ⚠
galactofuranosyltransferase lpg1-like protein
— OG7
LAEL147_000399400 ⚠
beta-galactofuranosyltransferase-like protein
— OG7
LAEL147_000774900 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000883800 ⚠
replication factor C, subunit 5, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000132600 ⚠
MORN repeat, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000418000 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000451600 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
LAEL147_000554100 ⚠
co-chaperone GrpE, putative
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000828800 ⚠
TLD, putative
— OG7
LAEL147_000841800 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
LAEL147_000020500 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000451500 ⚠
hypothetical protein
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000589400 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000745000 ⚠
geranylgeranyltransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.