LAEL147_000554100

co-chaperone GrpE, putative
Leishmania aethiopica L147 OG6: OG6_100642 OG7: OG7_0004892 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000575500
small glutamine-rich tetratricopeptide repeat
— OG6
LAEL147_000103200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LAEL147_000574300 ⚠
replication factor C, subunit 2, putative
— OG7
LAEL147_000304600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000246900 ⚠
ATPase family associated with various cellula
— OG7
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LAEL147_000460100 ⚠
replication factor C, subunit 4, putative
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000774900 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000863000 ⚠
Calponin homology (CH) domain containing prot
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000347900 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAEL147_000783400 ⚠
RNA-binding protein, putative
— OG7
LAEL147_000686600 ⚠
Ribosome assembly protein rrb1, putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000632300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000758600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000690900 ⚠
glycosyl hydrolase-like protein
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000632800 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000778500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000730400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000067300 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAEL147_000744300 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000800400 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LAEL147_000668700 ⚠
DNA mismatch repair protein MSH2, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000271200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000206000 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LAEL147_000285100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000426000 ⚠
Lsm7p protein, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000500700 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000221000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000522500 ⚠
heat shock protein 90, putative
— OG7
LAEL147_000254200 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000668200 ⚠
heat shock protein 83-17
— OG7
LAEL147_000152900 ⚠
aminopeptidase, putative
— OG7
LAEL147_000638000 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000553700 ⚠
nuclear movement protein, putative
— OG7
LAEL147_000269100 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LAEL147_000438500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000541800 ⚠
protein kinase, putative
— OG7
LAEL147_000354500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000153000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000518000 ⚠
Putative GTPase activating protein for Arf, p
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.