LAEL147_000800400

BRCA1 C Terminus (BRCT) domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_146478 OG7: OG7_0043662 100 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 100 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000696000
translation initiation factor IF-2, putative
— Both
LAEL147_000554100 ⚠
co-chaperone GrpE, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000460100 ⚠
replication factor C, subunit 4, putative
— OG7
LAEL147_000246900 ⚠
ATPase family associated with various cellula
— OG7
LAEL147_000304600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000574300 ⚠
replication factor C, subunit 2, putative
— OG7
LAEL147_000883800 ⚠
replication factor C, subunit 5, putative
— OG7
LAEL147_000745000 ⚠
geranylgeranyltransferase, putative
— OG7
LAEL147_000425700
hypothetical protein, conserved
— Both
LAEL147_000471300 ⚠
eukaryotic translation initiation factor eIF-
— OG7
LAEL147_000554200 ⚠
heat shock protein grpe
— Both
LAEL147_000502300
p21-C-terminal region-binding protein, putati
— Both
LAEL147_000449700
WD domain, G-beta repeat, putative
— Both
LAEL147_000105200
WD domain, G-beta repeat, putative
— Both
LAEL147_000168000 ⚠
WW domain containing protein, putative
— Both
LAEL147_000285100
hypothetical protein, conserved
— Both
LAEL147_000155800
Leucine Rich repeat, putative
— Both
LAEL147_000334900 ⚠
transcription factor-like protein
— Both
LAEL147_000693000
hypothetical protein, conserved
— Both
LAEL147_000686200
IQ calmodulin-binding motif containing protei
— Both
LAEL147_000015500 ⚠
ras-like small GTPases, putative
— OG6
LAEL147_000880100 ⚠
protein transport protein Sec23-like protein
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000828800 ⚠
TLD, putative
— OG7
LAEL147_000212800 ⚠
ecotin, putative
— OG7
LAEL147_000210800 ⚠
ecotin, putative
— OG7
LAEL147_000841800 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000744300 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000774900 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000628800 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000862600 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000594900 ⚠
ras-like small GTPases, putative
— OG6
LAEL147_000520800 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAEL147_000020500 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000632600 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LAEL147_000796900 ⚠
sm-f snRNP core complex protein, putative
— OG7
LAEL147_000559800 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LAEL147_000418000 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000254400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000507700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
LAEL147_000508800 ⚠
eukaryotic translation initiation factor 4e,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.