LAEL147_000471300

eukaryotic translation initiation factor eIF-4E, putative
Leishmania aethiopica L147 OG6: OG6_100627 OG7: OG7_0002303 217 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 217 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LAEL147_000496300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000496200 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LAEL147_000029300 ⚠
Vps51/Vps67, putative
— OG7
LAEL147_000291200 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LAEL147_000337300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LAEL147_000410500 ⚠
dehydrogenase-like protein
— OG7
LAEL147_000178200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000168000 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000254400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000507700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000449700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000212000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000087400 ⚠
alpha-adaptin-like protein
— OG7
LAEL147_000351700 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000826200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000815300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000696000 ⚠
translation initiation factor IF-2, putative
— OG7
LAEL147_000800400 ⚠
BRCA1 C Terminus (BRCT) domain containing pro
— OG7
LAEL147_000720300 ⚠
Protein of unknown function (DUF3808), putati
— OG7
LAEL147_000706400 ⚠
Conserved oligomeric complex COG6, putative
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000640000 ⚠
Phosphatidylethanolamine-binding protein, put
— OG7
LAEL147_000631700 ⚠
Vps23 core domain containing protein, putativ
— OG7
LAEL147_000696400 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000826100 ⚠
neurobeachin/beige protein, putative
— OG7
LAEL147_000867200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000373700 ⚠
clathrin coat assembly protein, putative
— OG7
LAEL147_000383700 ⚠
replication factor C, subunit 1, putative
— OG7
LAEL147_000270500 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LAEL147_000574300 ⚠
replication factor C, subunit 2, putative
— OG7
LAEL147_000304600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000246900 ⚠
ATPase family associated with various cellula
— OG7
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
LAEL147_000460100 ⚠
replication factor C, subunit 4, putative
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000479900 ⚠
aldo-keto reductase-like protein
— OG7
LAEL147_000744400 ⚠
adaptor gamma-1 chain, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000693000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000686200 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAEL147_000552200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000396000 ⚠
tubulin folding cofactor D, putative
— OG7
LAEL147_000096100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.