LAEL147_000774900

ubiquitin-protein ligase, putative
Leishmania aethiopica L147 OG6: OG6_146796 OG7: OG7_0002947 160 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 160 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000433000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000006700 ⚠
elongation factor 2
— OG7
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000809100 ⚠
elongation factor 2
— OG7
LAEL147_000809200 ⚠
small GTP-binding protein domain containing p
— OG7
LAEL147_000356500 ⚠
5'-AMP-activated protein kinase beta subunit,
— OG7
LAEL147_000570500 ⚠
Leucine-rich repeats, bacterial type, putativ
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000554100 ⚠
co-chaperone GrpE, putative
— OG7
LAEL147_000554200 ⚠
heat shock protein grpe
— OG7
LAEL147_000271200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000853500 ⚠
zinc carboxypeptidase, putative
— OG7
LAEL147_000104000 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000666300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LAEL147_000104100 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000162400 ⚠
ribonuclease mar1
— OG7
LAEL147_000692400 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000439400 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LAEL147_000064000 ⚠
GTPase, putative
— OG7
LAEL147_000354400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000285100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000228500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000426000 ⚠
Lsm7p protein, putative
— OG7
LAEL147_000432900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000243900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000103200 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LAEL147_000418000 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000559800 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LAEL147_000796900 ⚠
sm-f snRNP core complex protein, putative
— OG7
LAEL147_000005500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000632600 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LAEL147_000020500 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000853800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000150200 ⚠
chromatin binding protein, putative
— OG7
LAEL147_000632300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000552200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000828800 ⚠
TLD, putative
— OG7
LAEL147_000040100 ⚠
TLD domain protein, conserved
— OG7
LAEL147_000582400 ⚠
calmodulin-related protein, putative
— OG7
LAEL147_000274100 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAEL147_000143600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000105200 ⚠
WD domain, G-beta repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.