LAEL147_000632800

HECT-domain (ubiquitin-transferase), putative
Leishmania aethiopica L147 OG6: OG6_102181 OG7: OG7_0002947 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000243900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000460100 ⚠
replication factor C, subunit 4, putative
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000006700 ⚠
elongation factor 2
— OG7
LAEL147_000359700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000421800 ⚠
elongation factor 2-like protein
— OG7
LAEL147_000781900 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000809100 ⚠
elongation factor 2
— OG7
LAEL147_000809200 ⚠
small GTP-binding protein domain containing p
— OG7
LAEL147_000676000 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LAEL147_000570500 ⚠
Leucine-rich repeats, bacterial type, putativ
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000554100 ⚠
co-chaperone GrpE, putative
— OG7
LAEL147_000066700 ⚠
Vta1 like, putative
— OG7
LAEL147_000229400 ⚠
aspartate carbamoyltransferase, putative
— OG7
LAEL147_000579300 ⚠
homoserine kinase, putative
— OG7
LAEL147_000853500 ⚠
zinc carboxypeptidase, putative
— OG7
LAEL147_000731200 ⚠
zinc carboxypeptidase, putative
— OG7
LAEL147_000666300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LAEL147_000104000 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000104200 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LAEL147_000104100 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000162400 ⚠
ribonuclease mar1
— OG7
LAEL147_000692400 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000060900 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAEL147_000439400 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LAEL147_000064000 ⚠
GTPase, putative
— OG7
LAEL147_000061100 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAEL147_000008500 ⚠
3-mercaptopyruvate sulfurtransferase
— OG7
LAEL147_000359200 ⚠
Galactose oxidase, central domain containing
— OG7
LAEL147_000354400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000609000 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
LAEL147_000464500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000228500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000026000 ⚠
ubiquitin activating enzyme, putative
— OG7
LAEL147_000418000 ⚠
LSM domain containing protein, putative
— OG7
LAEL147_000432900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000061600 ⚠
hydrogenase, putative
— OG7
LAEL147_000429900 ⚠
nucleotide binding protein-like protein
— OG7
LAEL147_000318800 ⚠
nucleotide-binding protein, putative
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000828800 ⚠
TLD, putative
— OG7
LAEL147_000143600 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAEL147_000269700 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAEL147_000274100 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.