LAEL147_000781900

ubiquitin-activating enzyme E1, putative
Leishmania aethiopica L147 OG6: OG6_100444 OG7: OG7_0003530 177 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 177 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000221000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000745300 ⚠
ubiquitin hydrolase, putative
— Both
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000773600 ⚠
hypothetical protein, conserved
— Both
LAEL147_000043700 ⚠
Ubiquitin-like domain containing protein, put
— Both
LAEL147_000773300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000318800 ⚠
nucleotide-binding protein, putative
— Both
LAEL147_000429900 ⚠
nucleotide binding protein-like protein
— Both
LAEL147_000508500 ⚠
MRP protein-like protein
— OG6
LAEL147_000746800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000298600 ⚠
hypothetical protein, conserved
— Both
LAEL147_000227600 ⚠
Met-10+ like-protein, putative
— Both
LAEL147_000031500 ⚠
casein kinase II, alpha chain, putative
— OG6
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LAEL147_000179900 ⚠
protein kinase, putative
— Both
LAEL147_000178700 ⚠
protein kinase, putative
— Both
LAEL147_000756700 ⚠
proteasome activator protein pa26, putative
— Both
LAEL147_000323300 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LAEL147_000344000 ⚠
Beta-lactamase superfamily domain containing
— Both
LAEL147_000343900 ⚠
Beta-lactamase superfamily domain containing
— Both
LAEL147_000027900 ⚠
Creatinase/Prolidase N-terminal domain contai
— Both
LAEL147_000425900 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
LAEL147_000043500 ⚠
TatD related DNase, putative
— Both
LAEL147_000061600 ⚠
hydrogenase, putative
— Both
LAEL147_000095500 ⚠
HEAT-like repeat, putative
— OG7
LAEL147_000137200 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LAEL147_000006700 ⚠
elongation factor 2
— OG7
LAEL147_000812300 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LAEL147_000347900 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAEL147_000432900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000243900 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000536300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000447100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000245000 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000005500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000853800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000666300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LAEL147_000228500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000570500 ⚠
Leucine-rich repeats, bacterial type, putativ
— OG7
LAEL147_000042900 ⚠
DEAD/DEAH box helicase, putative
— OG7
LAEL147_000632800 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000067300 ⚠
Mitochondrial glycoprotein, putative
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000500700 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000235500 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LAEL147_000638000 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LAEL147_000016300 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LAEL147_000222700 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.