LAEL147_000245000

Dihydrouridine synthase (Dus), putative
Leishmania aethiopica L147 OG6: OG6_101202 OG7: OG7_0002064 220 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 220 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000583300 ⚠
DNA ligase I, putative
— Both
LAEL147_000536300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000781900 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000439400 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LAEL147_000060900 ⚠
50S ribosome-binding GTPase, putative
— OG7
LAEL147_000692400 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000228400 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000301600 ⚠
tubulin-tyrosine ligase, putative
— OG7
LAEL147_000480700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000517200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAEL147_000570600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000801500 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000162400 ⚠
ribonuclease mar1
— OG7
LAEL147_000653100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000104100 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000104200 ⚠
mitochondrial associated ribonuclease, putati
— OG7
LAEL147_000150000 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000104000 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LAEL147_000579300 ⚠
homoserine kinase, putative
— OG7
LAEL147_000447200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000447100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000229400 ⚠
aspartate carbamoyltransferase, putative
— OG7
LAEL147_000066700 ⚠
Vta1 like, putative
— OG7
LAEL147_000809200 ⚠
small GTP-binding protein domain containing p
— OG7
LAEL147_000809100 ⚠
elongation factor 2
— OG7
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
LAEL147_000676000 ⚠
Protein prenyltransferase alpha subunit repea
— OG7
LAEL147_000570500 ⚠
Leucine-rich repeats, bacterial type, putativ
— OG7
LAEL147_000683300 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LAEL147_000632800 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000150200 ⚠
chromatin binding protein, putative
— OG7
LAEL147_000744300 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000721600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000730300 ⚠
methyltransferase-like protein
— OG7
LAEL147_000607600 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LAEL147_000433000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000354400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000609000 ⚠
Fungal tRNA ligase phosphodiesterase domain c
— OG7
LAEL147_000006700 ⚠
elongation factor 2
— OG7
LAEL147_000035200 ⚠
Heat shock protein 100 kDa
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000359700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000421800 ⚠
elongation factor 2-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.