LAEL147_000583300

DNA ligase I, putative
Leishmania aethiopica L147 OG6: OG6_100906 OG7: OG7_0002598 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000606500 ⚠
dihydrouridine synthase (Dus), putative
— Both
LAEL147_000715800 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000043700 ⚠
Ubiquitin-like domain containing protein, put
— Both
LAEL147_000812300 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LAEL147_000245000 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAEL147_000653100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000062000 ⚠
hypothetical protein, conserved
— Both
LAEL147_000401300 ⚠
cleavage and polyadenylation specificity fact
— Both
LAEL147_000778100 ⚠
acyl-CoA dehydrogenase, putative
— Both
LAEL147_000753500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000834900 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— Both
LAEL147_000415300 ⚠
Peptide chain release factor 1, mitochondrial
— Both
LAEL147_000259100 ⚠
alpha glucosidase II subunit, putative
— Both
LAEL147_000305200 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
LAEL147_000283400 ⚠
ABC transport system ATP-binding protein, put
— Both
LAEL147_000581700 ⚠
UV excision repair RAD23-like protein
— Both
LAEL147_000258200 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LAEL147_000463600 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000579600 ⚠
S-adenosylmethionine decarboxylase
— Both
LAEL147_000498800 ⚠
phosphonopyruvate decarboxylase-like protein
— Both
LAEL147_000346000 ⚠
translation initiation factor IF-2, putative
— Both
LAEL147_000345100 ⚠
translation initiation factor IF-2, putative
— Both
LAEL147_000031500
casein kinase II, alpha chain, putative
— OG6
LAEL147_000067600 ⚠
hypothetical protein, conserved
— Both
LAEL147_000348700 ⚠
alanyl-tRNA synthetase, putative
— Both
LAEL147_000485900 ⚠
DIS3-like exonuclease, putative
— Both
LAEL147_000323300 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LAEL147_000501200 ⚠
replication factor A, 51kDa subunit, putative
— Both
LAEL147_000344000 ⚠
Beta-lactamase superfamily domain containing
— Both
LAEL147_000343900 ⚠
Beta-lactamase superfamily domain containing
— Both
LAEL147_000371800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000664000 ⚠
Gar1/Naf1 RNA binding region containing prote
— Both
LAEL147_000043500 ⚠
TatD related DNase, putative
— Both
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— Both
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— Both
LAEL147_000484800 ⚠
rrp44p homologue, putative
— OG7
LAEL147_000049200 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LAEL147_000137200 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LAEL147_000447100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000104000 ⚠
Isochorismatase family, putative
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LAEL147_000338800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAEL147_000681100 ⚠
protein kinase, putative
— OG7
LAEL147_000884600 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
LAEL147_000553700 ⚠
nuclear movement protein, putative
— OG7
LAEL147_000235500 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LAEL147_000673500 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.