LAEL147_000264000

Zn-finger in Ran binding protein and others/FYVE zinc finger containing protein, putative
Leishmania aethiopica L147 OG6: OG6_139898 OG7: OG7_0001169 247 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 247 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000155800 ⚠
Leucine Rich repeat, putative
— Both
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— Both
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000392200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000628700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000745000 ⚠
geranylgeranyltransferase, putative
— OG7
LAEL147_000871100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000676900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000745600 ⚠
GRIP domain containing protein, putative
— OG7
LAEL147_000841200 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LAEL147_000589400 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAEL147_000718600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000870000 ⚠
beta-adaptin protein, putative
— OG7
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LAEL147_000832600 ⚠
Spc97 / Spc98 family, putative
— OG7
LAEL147_000738100 ⚠
Zinc finger domain containing protein, putati
— OG7
LAEL147_000572300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000590100 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LAEL147_000650000 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000688600 ⚠
mitogen-activated protein kinase, putative
— OG7
LAEL147_000618400 ⚠
acetyl-CoA carboxylase, putative
— OG7
LAEL147_000866500 ⚠
glycosyl hydrolase, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000835500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000840200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000497600 ⚠
Cell division control protein 48, putative
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000560500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000598300 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000326700 ⚠
adenylate kinase, putative
— OG7
LAEL147_000177000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000281800 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
LAEL147_000742100 ⚠
phosphomannomutase-like protein
— OG7
LAEL147_000646800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000378400 ⚠
Leucine Rich repeats (2 copies)/Leucine rich
— OG7
LAEL147_000251900 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000636100 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LAEL147_000369300 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LAEL147_000014400 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000237600 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LAEL147_000313600 ⚠
Leucine Rich repeat/CHAT domain containing pr
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000149700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000351700 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.