LAEL147_000598300

Protein of unknown function (DUF3638)/Protein of unknown function (DUF3645)/Zn-finger in Ran binding protein and others, putative
Leishmania aethiopica L147 OG6: OG6_111983 OG7: OG7_0009773 187 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 187 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000866500
glycosyl hydrolase, putative
— Both
LAEL147_000724600
Glycosyl hydrolase family 65 central catalyti
— Both
LAEL147_000371100
Csl4p homologue, putative
— Both
LAEL147_000266100
hypothetical protein, conserved
— +2 more Both
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000058700 ⚠
casein kinase I, putative
— OG7
LAEL147_000583700 ⚠
casein kinase 1 isoform 2, putative
— OG7
LAEL147_000473300 ⚠
casein kinase I-like protein
— OG7
LAEL147_000733500 ⚠
protein kinase, putative
— OG7
LAEL147_000150000 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000759500 ⚠
casein kinase I, putative
— OG7
LAEL147_000382900 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LAEL147_000801400 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LAEL147_000507600 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LAEL147_000695500 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LAEL147_000062700 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LAEL147_000653400 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LAEL147_000686900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000868200 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LAEL147_000252000 ⚠
formin, putative
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000077800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000157100 ⚠
adaptin-related protein-like protein
— OG7
LAEL147_000614700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LAEL147_000205100 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000465900 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
LAEL147_000573200 ⚠
AAA family ATPase-like protein
— OG7
LAEL147_000713700 ⚠
myosin IB heavy chain, putative
— OG7
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LAEL147_000165500
hypothetical protein, conserved
— OG7
LAEL147_000738700 ⚠
peroxisome biosynthesis protein-like protein
— OG7
LAEL147_000224900 ⚠
peroxisome assembly protein, putative
— OG7
LAEL147_000283400 ⚠
ABC transport system ATP-binding protein, put
— OG7
LAEL147_000309600 ⚠
cell division cycle protein-like protein
— OG7
LAEL147_000156000 ⚠
ATPase, putative
— OG7
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000482500 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
LAEL147_000801500 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000884500 ⚠
beta-adaptin, putative
— OG7
LAEL147_000392200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000870000 ⚠
beta-adaptin protein, putative
— OG7
LAEL147_000813900 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LAEL147_000279400 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LAEL147_000607700 ⚠
polyubiquitin, putative
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.