LAEL147_000724600

Glycosyl hydrolase family 65 central catalytic domain/Glycosyl hydrolase family 65, C-terminal domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_143485 OG7: OG7_0042752 121 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 121 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000598300
Protein of unknown function (DUF3638)/Protein
— Both
LAEL147_000866500
glycosyl hydrolase, putative
— Both
LAEL147_000266100
hypothetical protein, conserved
— +2 more Both
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000156000 ⚠
ATPase, putative
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LAEL147_000870000 ⚠
beta-adaptin protein, putative
— OG7
LAEL147_000884500 ⚠
beta-adaptin, putative
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000157100 ⚠
adaptin-related protein-like protein
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LAEL147_000868200 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000686900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000759500 ⚠
casein kinase I, putative
— OG7
LAEL147_000733500 ⚠
protein kinase, putative
— OG7
LAEL147_000473300 ⚠
casein kinase I-like protein
— OG7
LAEL147_000583700 ⚠
casein kinase 1 isoform 2, putative
— OG7
LAEL147_000058700 ⚠
casein kinase I, putative
— OG7
LAEL147_000416600 ⚠
casein kinase I, putative
— OG7
LAEL147_000842500 ⚠
cullin-like protein
— OG7
LAEL147_000236400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAEL147_000834800 ⚠
Cullin protein neddylation domain containing
— OG7
LAEL147_000398800 ⚠
cullin-like protein-like protein
— OG7
LAEL147_000826100 ⚠
neurobeachin/beige protein, putative
— OG7
LAEL147_000614300 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000696400 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000635700 ⚠
RNA guanylyltransferase, putative
— OG7
LAEL147_000342900 ⚠
Galactose oxidase, central domain containing
— OG7
LAEL147_000876500 ⚠
Kelch motif containing protein, putative
— OG7
LAEL147_000396800 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAEL147_000225100 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LAEL147_000498900 ⚠
Galactose oxidase, central domain containing
— OG7
LAEL147_000378300 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LAEL147_000505200 ⚠
Galactose oxidase, central domain containing
— OG7
LAEL147_000823200 ⚠
Kelch motif containing protein, putative
— OG7
LAEL147_000077800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000294800 ⚠
kelch domain-containing protein
— OG7
LAEL147_000392200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000063400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LAEL147_000327600 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LAEL147_000786500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LAEL147_000224500 ⚠
AAA domain containing protein, putative
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.