LAEL147_000218900

glutamate dehydrogenase
Leishmania aethiopica L147 OG6: OG6_106160 OG7: OG7_0011174 123 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 123 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000692300 ⚠
heat shock protein, putative
— +1 more OG7
LAEL147_000522500 ⚠
heat shock protein 90, putative
— +6 more Both
LAEL147_000668200 ⚠
heat shock protein 83-17
— +6 more Both
LAEL147_000291200 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LAEL147_000093300
hypothetical protein, conserved
— Both
LAEL147_000571000
SET domain containing protein, putative
— Both
LAEL147_000581900
MORN repeat, putative
— Both
LAEL147_000157200
pyruvate phosphate dikinase, putative
— Both
LAEL147_000639100
hypothetical protein, conserved
— Both
LAEL147_000851800
S-adenosylhomocysteine hydrolase
— Both
LAEL147_000070300 ⚠
MORN repeat, putative
— Both
LAEL147_000109300
Beta-lactamase superfamily domain containing
— Both
LAEL147_000782100
glycerol kinase, glycosomal, putative
— Both
LAEL147_000376600 ⚠
fumarate hydratase, putative
— Both
LAEL147_000536200 ⚠
fumarate hydratase, putative
— Both
LAEL147_000630400
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LAEL147_000653300
nucleoside diphosphate kinase b
— Both
LAEL147_000049400
hypothetical protein, conserved
— Both
LAEL147_000198800
hypothetical protein
— OG6
LAEL147_000173200
WD40 repeats, putative
— Both
LAEL147_000219300 ⚠
AhpC/TSA family/C-terminal domain of 1-Cys pe
— Both
LAEL147_000219200 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000350900 ⚠
peroxidoxin
— Both
LAEL147_000219400 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000217900
protein phosphatase 2A regulatory subunit, pu
— Both
LAEL147_000023400 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LAEL147_000305600 ⚠
hypothetical protein
— OG6
LAEL147_000252400
Mak10 subunit, NatC N(alpha)-terminal acetylt
— Both
LAEL147_000305800 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000305700 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LAEL147_000050400 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LAEL147_000763700
threonyl-tRNA synthetase, putative
— Both
LAEL147_000073400
hypothetical protein, conserved
— Both
LAEL147_000726700 ⚠
Elongation factor Tu GTP binding domain conta
— OG7
LAEL147_000736400 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LAEL147_000744300 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAEL147_000857100 ⚠
ubiquitin protein ligase, putative
— OG7
LAEL147_000774900 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000315800 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LAEL147_000379900 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000698900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000629100 ⚠
cyclin 9, putative
— OG7
LAEL147_000243800 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000559700 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000320600 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LAEL147_000745300 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000206000 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LAEL147_000802200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LAEL147_000526900 ⚠
PSP1 C-terminal conserved region containing p
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.