LAEL147_000157200

pyruvate phosphate dikinase, putative
Leishmania aethiopica L147 OG6: OG6_100727 OG7: OG7_0004964 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000338700 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LAEL147_000071800 ⚠
histone H4
— Both
LAEL147_000311600 ⚠
Core histone H2A/H2B/H3/H4, putative
— Both
LAEL147_000207600 ⚠
histone H4
— Both
LAEL147_000749400 ⚠
histone H4
— Both
LAEL147_000037500
hypothetical protein, conserved
— Both
LAEL147_000508100
vacuolar ATP synthase subunit b, putative
— Both
LAEL147_000024900
DNA-damage inducible protein DDI1-like protei
— Both
LAEL147_000076200
glutamine synthetase, putative
— Both
LAEL147_000761500 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000757700 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000426300
pyridoxal phosphate containing glycine decarb
— Both
LAEL147_000219300 ⚠
AhpC/TSA family/C-terminal domain of 1-Cys pe
— Both
LAEL147_000219200 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000851800
S-adenosylhomocysteine hydrolase
— Both
LAEL147_000354700
(H+)-ATPase G subunit, putative
— Both
LAEL147_000218900
glutamate dehydrogenase
— Both
LAEL147_000842900
ATP synthase, putative
— Both
LAEL147_000740900
vacuolar ATP synthase catalytic subunit A, pu
— Both
LAEL147_000761400 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000350900 ⚠
peroxidoxin
— Both
LAEL147_000096500 ⚠
flavoprotein subunit-like protein
— Both
LAEL147_000219400 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000703200
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LAEL147_000037800
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LAEL147_000031000
Soluble NSF attachment protein, SNAP, putativ
— Both
LAEL147_000058800
hypothetical protein, conserved
— Both
LAEL147_000314300 ⚠
Hexokinase, putative
— Both
LAEL147_000314200 ⚠
hexokinase, putative
— Both
LAEL147_000248000 ⚠
Acyl CoA binding protein, putative
— OG7
LAEL147_000728700 ⚠
acyl-CoA binding protein, putative
— OG7
LAEL147_000247800 ⚠
Acyl CoA binding protein, putative
— OG7
LAEL147_000284300 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LAEL147_000394500 ⚠
cyclin 11, putative
— OG7
LAEL147_000472400 ⚠
zinc finger containing protein, putative
— OG7
LAEL147_000537400 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000150200 ⚠
chromatin binding protein, putative
— OG7
LAEL147_000809800 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LAEL147_000211500 ⚠
RNA pseudouridylate synthase, putative
— OG7
LAEL147_000721600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000793700 ⚠
elongation factor 1-alpha, putative
— OG7
LAEL147_000066500 ⚠
CYC2-like cyclin, putative
— OG7
LAEL147_000347400 ⚠
fk506-binding protein 1-like protein
— OG7
LAEL147_000064000 ⚠
GTPase, putative
— OG7
LAEL147_000439400 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LAEL147_000692400 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000290800 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LAEL147_000036400 ⚠
Met-10+ like-protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.