LAEL147_000181500

N(2), N(2)-dimethylguanosine tRNA methyltransferase, putative
Leishmania aethiopica L147 OG6: OG6_101071 OG7: OG7_0004550 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000740900
vacuolar ATP synthase catalytic subunit A, pu
— Both
LAEL147_000808700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LAEL147_000331800 ⚠
protein kinase, putative
— Both
LAEL147_000011700
hypothetical protein, conserved
— Both
LAEL147_000050400 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LAEL147_000096500 ⚠
flavoprotein subunit-like protein
— Both
LAEL147_000096100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LAEL147_000761400 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000842900
ATP synthase, putative
— Both
LAEL147_000209200 ⚠
serine/threonine-protein kinase, putative
— OG7
LAEL147_000855700
paraflagellar rod component, putative
— OG6
LAEL147_000044000 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LAEL147_000560000
Zinc finger, C3HC4 type (RING finger) contain
— Both
LAEL147_000550000
kinesin, putative
— OG6
LAEL147_000705700 ⚠
tRNA pseudouridine synthase, putative
— Both
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000270500 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000429800 ⚠
pseudouridylate synthase-like protein
— OG7
LAEL147_000202300 ⚠
protein kinase, putative
— OG7
LAEL147_000428700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LAEL147_000199500 ⚠
protein kinase, putative
— OG7
LAEL147_000807900 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LAEL147_000562700 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LAEL147_000067700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000132100
hypothetical protein, conserved
— OG7
LAEL147_000600600
hypothetical protein, conserved
— OG7
LAEL147_000868500
branch point binding protein, putative
— Both
LAEL147_000855900 ⚠
protein kinase-like protein
— OG7
LAEL147_000284800 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LAEL147_000812500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000685400 ⚠
dual-specificity protein kinase, putative
— OG7
LAEL147_000517500 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LAEL147_000768600 ⚠
protein kinase-like protein
— OG7
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LAEL147_000339900
Uncharacterised protein family UPF0066, putat
— Both
LAEL147_000396000
tubulin folding cofactor D, putative
— Both
LAEL147_000305600 ⚠
hypothetical protein
— OG6
LAEL147_000270400 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— Both
LAEL147_000761500 ⚠
NADH-dependent fumarate reductase, putative
— Both
LAEL147_000024900
DNA-damage inducible protein DDI1-like protei
— Both
LAEL147_000517800 ⚠
TPR repeat, putative
— Both
LAEL147_000340500
guide RNA associated protein, GAP2, putative
— Both
LAEL147_000198800
hypothetical protein
— OG6
LAEL147_000780600 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000511500 ⚠
Hsp70 protein, putative
— OG6
LAEL147_000512000 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000508100
vacuolar ATP synthase subunit b, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.