LAEL147_000373600

pyruvate dehydrogenase (lipoamide) kinase, putative
Leishmania aethiopica L147 OG6: OG6_146742 OG7: OG7_0002830 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000878700 ⚠
poly(A)-specific ribonuclease PARN, putative
— +1 more Both
LAEL147_000358000 ⚠
poly(A)-specific ribonuclease PARN, putative
— +1 more Both
LAEL147_000164700 ⚠
cysteinyl-tRNA synthetase, putative
— +1 more Both
LAEL147_000285000 ⚠
phenylalanyl-tRNA synthetase, putative
— +1 more Both
LAEL147_000396000 ⚠
tubulin folding cofactor D, putative
— +1 more Both
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
LAEL147_000743400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAEL147_000773700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000540600 ⚠
aspartyl aminopeptidase, putative
— Both
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000295600 ⚠
developmentally regulated phosphoprotein-like
— Both
LAEL147_000601900 ⚠
Leucine-rich repeat - CC (cysteine-containing
— Both
LAEL147_000836900 ⚠
related to multifunctional cyclin-dependent k
— OG7
LAEL147_000502300 ⚠
p21-C-terminal region-binding protein, putati
— Both
LAEL147_000760100 ⚠
hypothetical protein, conserved
— Both
LAEL147_000380200 ⚠
PPPDE putative peptidase domain containing pr
— Both
LAEL147_000533600 ⚠
MORN repeat, putative
— Both
LAEL147_000378400 ⚠
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LAEL147_000011200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000245500 ⚠
Ring finger domain containing protein, putati
— Both
LAEL147_000098200 ⚠
Domain of unknown function (DUF3437), putativ
— Both
LAEL147_000394700 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LAEL147_000268400 ⚠
5-oxoprolinase, putative
— Both
LAEL147_000694000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000045900 ⚠
MORN repeat, putative
— OG7
LAEL147_000070300 ⚠
MORN repeat, putative
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000808700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LAEL147_000044000 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LAEL147_000096100 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LAEL147_000774500 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000468000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000164100 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000175500 ⚠
Domain of unknown function (DUF4200), putativ
— OG7
LAEL147_000570800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000132600 ⚠
MORN repeat, putative
— OG7
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAEL147_000451600 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000635400 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAEL147_000224600 ⚠
arginine N-methyltransferase, type I
— OG7
LAEL147_000819600 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LAEL147_000794500 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LAEL147_000511500 ⚠
Hsp70 protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.