LAEL147_000098200

Domain of unknown function (DUF3437), putative
Leishmania aethiopica L147 OG6: OG6_199775 OG7: OG7_0052363 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000156100
PUB domain containing protein, putative
— Both
LAEL147_000696000
translation initiation factor IF-2, putative
— Both
LAEL147_000694800 ⚠
dynein intermediate chain, putative
— Both
LAEL147_000195000 ⚠
cystathionine beta-lyase-like protein
— Both
LAEL147_000214500
hypothetical protein, conserved
— Both
LAEL147_000378400
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LAEL147_000164700
cysteinyl-tRNA synthetase, putative
— Both
LAEL147_000168000 ⚠
WW domain containing protein, putative
— Both
LAEL147_000105200
WD domain, G-beta repeat, putative
— Both
LAEL147_000880100 ⚠
protein transport protein Sec23-like protein
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000471300 ⚠
eukaryotic translation initiation factor eIF-
— OG7
LAEL147_000883800 ⚠
replication factor C, subunit 5, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000507700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000132600 ⚠
MORN repeat, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAEL147_000508800 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LAEL147_000773700 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LAEL147_000451600 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
LAEL147_000203600 ⚠
WD40 repeats, putative
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000743400 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000460100 ⚠
replication factor C, subunit 4, putative
— OG7
LAEL147_000082500 ⚠
TLD, putative
— OG7
LAEL147_000828800 ⚠
TLD, putative
— OG7
LAEL147_000841800 ⚠
ATP-dependent RNA helicase, putative
— OG7
LAEL147_000376200 ⚠
dynein intermediate-chain-like protein
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
LAEL147_000451500 ⚠
hypothetical protein
— OG7
LAEL147_000783900 ⚠
replication factor C, subunit 3, putative
— OG7
LAEL147_000212800 ⚠
ecotin, putative
— OG7
LAEL147_000295600 ⚠
developmentally regulated phosphoprotein-like
— OG7
LAEL147_000628800 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000520800 ⚠
NF-X1 type zinc finger containing protein, pu
— OG7
LAEL147_000635400 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LAEL147_000210800 ⚠
ecotin, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAEL147_000862600 ⚠
Leucine rich repeat, putative
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000246900 ⚠
ATPase family associated with various cellula
— OG7
LAEL147_000515400 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000254400 ⚠
WW domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.