LAEL147_000659300

exosome-associated protein 2, putative

Leishmania aethiopica L147 OG6: OG6_100420 OG7: OG7_0002825 75 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 75 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000190100 ⚠ exosome complex exonuclease, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010369 OG6 Tb927.6.670 ↔ Tb927.7.4670 OG6 Tb927.11.16600 ↔ Tb927.7.4670 OG6 LdBPK_140010.1 ↔ LdBPK_221430.1 +4 more	Both
LAEL147_000189700 ⚠ exosome complex exonuclease, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010369 OG6 Tb927.6.670 ↔ Tb927.7.4670 OG6 Tb927.11.16600 ↔ Tb927.7.4670 OG6 LdBPK_140010.1 ↔ LdBPK_221430.1 +4 more	Both
LAEL147_000031100 ⚠ ribosomal RNA processing protein, putative	—	OG6 LdBPK_020290.1 ↔ LdBPK_221430.1 OG6 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 +2 more	Both
LAEL147_000842000 ⚠ exosome complex exonuclease RRP41, putative	—	OG6 Tb927.10.7450 ↔ Tb927.6.670 OG6 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 +2 more	Both
LAEL147_000047600 ⚠ exosome complex exonuclease RRP40, putative	—	OG6 LdBPK_040130.1 ↔ LdBPK_221430.1 OG6 Tb927.6.670 ↔ Tb927.9.7070 OG6 Tb927.11.16600 ↔ Tb927.9.7070 OG7 Tb927.6.670 ↔ Tb927.9.7070 +2 more	Both
LAEL147_000862700 ⚠ exosome-associated protein 4, putative	—	OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 LdBPK_020290.1 ↔ LdBPK_221430.1	OG7
LAEL147_000734200 ⚠ exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG6 LdBPK_044330.1 ↔ LdBPK_221430.1 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG7 LdBPK_044330.1 ↔ LdBPK_221430.1	Both
LAEL147_000711900 ⚠ elongation factor 1-beta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LAEL147_000438100 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LAEL147_000371100 ⚠ Csl4p homologue, putative	—	OG6 Tb927.11.16600 ↔ Tb927.5.1200 OG6 Tb927.5.1200 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.5.1200 OG7 Tb927.5.1200 ↔ Tb927.6.670	Both
LAEL147_000511500 ⚠ Hsp70 protein, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LAEL147_000349200 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 Tb927.11.16600 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.6.670	Both
LAEL147_000512000 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710	OG6
LAEL147_000494700 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LAEL147_000511600 ⚠ heat-shock protein hsp70, putative	—	OG6 Tb927.6.670 ↔ Tb927.7.710 OG6 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 +1 more	Both
LAEL147_000482400 ⚠ proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
LAEL147_000148500 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LAEL147_000711600 ⚠ elongation factor 1-beta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LAEL147_000822800 ⚠ translation elongation factor 1-beta, putativ	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LAEL147_000711800 ⚠ EF-1 guanine nucleotide exchange domain conta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LAEL147_000773000 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001893	OG6
LAEL147_000281800 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010718	OG7
LAEL147_000189200 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LAEL147_000467800 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LAEL147_000790500 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LAEL147_000106200 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	OG7
LAEL147_000886200 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LAEL147_000193200 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LAEL147_000333600 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LAEL147_000824800 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LAEL147_000841800 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004479	OG7
LAEL147_000006000 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LAEL147_000456200 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LAEL147_000799400 ⚠ Hsp70 protein, putative	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LAEL147_000025300 ⚠ HSP70-like protein	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LAEL147_000430400 ⚠ Conserved hypothetical ATP binding protein, p	—	OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	OG7
LAEL147_000587800 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LAEL147_000434600 ⚠ heat shock 70 protein-like protein	—	OG7 Tb927.6.670 ↔ Tb927.7.710 OG7 Tb927.11.16600 ↔ Tb927.7.710 OG7 Tb927.10.12710 ↔ Tb927.6.670	OG7
LAEL147_000292700 ⚠ DNA-directed RNA polymerase polypeptide, puta	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LAEL147_000686900 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
LAEL147_000198800 ⚠ hypothetical protein	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_008440	OG6
LAEL147_000657300 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
LAEL147_000388100 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009798 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009798	Both
LAEL147_000706200 ⚠ eukaryotic translation initiation factor 5, p	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LAEL147_000790300 ⚠ proteasome beta 2 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LAEL147_000618400 ⚠ acetyl-CoA carboxylase, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_002772 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_002772	Both
LAEL147_000800800 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LAEL147_000111300 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
LAEL147_000162000 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LAEL147_000203700 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both

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