LAEL147_000203700

'Cold-shock' DNA-binding domain containing protein, putative

Leishmania aethiopica L147 OG6: OG6_147036 OG7: OG7_0042945 73 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 73 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000162000 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	Both
LAEL147_000886200 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LAEL147_000185800 ⚠ AAA domain/Dpy-30 motif containing protein, p	—	OG7 TCSYLVIO_000435 ↔ TCSYLVIO_010606	OG7
LAEL147_000283400 ⚠ ABC transport system ATP-binding protein, put	—	OG7 TCSYLVIO_004518 ↔ TCSYLVIO_010606	OG7
LAEL147_000668100 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_004518 ↔ TCSYLVIO_010606	OG7
LAEL147_000106200 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	OG7
LAEL147_000173900 ⚠ mitochondrial DNA polymerase I protein B, put	—	OG7 TCSYLVIO_003485 ↔ TCSYLVIO_010606	OG7
LAEL147_000045900 ⚠ MORN repeat, putative	—	OG7 TCSYLVIO_001987 ↔ TCSYLVIO_010606	OG7
LAEL147_000148500 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LAEL147_000006000 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LAEL147_000790500 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LAEL147_000426100 brix domain containing-like protein	—	OG6 TCSYLVIO_000956 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000956 ↔ TCSYLVIO_010606	Both
LAEL147_000657300 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_005312 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	Both
LAEL147_000491500 oxidoreductase-like protein	—	OG6 TCSYLVIO_002566 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_002566 ↔ TCSYLVIO_010606	Both
LAEL147_000188900 ⚠ mitochondrial DNA polymerase I protein D, put	—	OG6 TCSYLVIO_003485 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003485 ↔ TCSYLVIO_010606	Both
LAEL147_000482400 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010606	Both
LAEL147_000081400 lipin, putative	—	OG6 TCSYLVIO_001856 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001856 ↔ TCSYLVIO_010606	Both
LAEL147_000800800 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_005678 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LAEL147_000475200 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_000435 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000435 ↔ TCSYLVIO_010606	Both
LAEL147_000468000 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LAEL147_000301800 ⚠ N-ethylmaleimide-sensitive factor, putative	—	OG7 Tb927.11.1680 ↔ Tb927.7.3810	OG7
LAEL147_000745300 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_007047 ↔ TCSYLVIO_010606	OG7
LAEL147_000767200 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_007047 ↔ TCSYLVIO_010606	OG7
LAEL147_000200900 ⚠ RNA editing 3' terminal uridylyl transferase	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LAEL147_000429500 ⚠ RET2, RNA editing complex MP57	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LAEL147_000489600 ⚠ RNA polymerase I	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LAEL147_000825400 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
LAEL147_000164100 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LAEL147_000111300 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LAEL147_000774500 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LAEL147_000193200 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LAEL147_000333600 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LAEL147_000824800 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LAEL147_000456200 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LAEL147_000841800 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_010606	OG7
LAEL147_000189200 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LAEL147_000467800 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LAEL147_000653600 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_010606	Both
LAEL147_000659300 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both
LAEL147_000686900 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LAEL147_000868200 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LAEL147_000266100 hypothetical protein, conserved	—	OG6 TCSYLVIO_006208 ↔ TCSYLVIO_010606 OG6 TCSYLVIO_006209 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006208 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006209 ↔ TCSYLVIO_010606	Both
LAEL147_000357500 hypothetical protein, conserved	—	OG6 TCSYLVIO_000050 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000050 ↔ TCSYLVIO_010606	Both
LAEL147_000734200 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_010606	Both
LAEL147_000042900 ⚠ DEAD/DEAH box helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_010606	Both
LAEL147_000477600 ⚠ Thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_010606	Both
LAEL147_000349200 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both
LAEL147_000579100 kinesin, putative	—	OG6 TCSYLVIO_003336 ↔ TCSYLVIO_010606	OG6
LAEL147_000690900 glycosyl hydrolase-like protein	—	OG6 TCSYLVIO_003461 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003461 ↔ TCSYLVIO_010606	Both
LAEL147_000531100 hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_010606	Both

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