LAEL147_000106200

ribose-phosphate pyrophosphokinase, putative
Leishmania aethiopica L147 OG6: OG6_145869 OG7: OG7_0002319 173 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 173 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000618400 ⚠
acetyl-CoA carboxylase, putative
— +5 more Both
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— +4 more Both
LAEL147_000868200 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
LAEL147_000686900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
LAEL147_000614300 ⚠
RNA polymerase ii largest subunit
— Both
LAEL147_000014400 ⚠
RNA polymerase ii largest subunit
— Both
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— Both
LAEL147_000237600 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LAEL147_000324700 ⚠
T-complex protein 1, delta subunit, putative
— +2 more OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000090000 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000236400 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LAEL147_000369300 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000826100 ⚠
neurobeachin/beige protein, putative
— OG7
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000834800 ⚠
Cullin protein neddylation domain containing
— OG7
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LAEL147_000870000 ⚠
beta-adaptin protein, putative
— OG7
LAEL147_000696400 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000652900 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAEL147_000224500 ⚠
AAA domain containing protein, putative
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000774500 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000515800 ⚠
DNA-directed RNA polymerase I-like protein
— OG7
LAEL147_000392200 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000884500 ⚠
beta-adaptin, putative
— OG7
LAEL147_000821900 ⚠
adenylate kinase, putative
— OG7
LAEL147_000056000 ⚠
adenylate kinase, putative
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LAEL147_000029000 ⚠
phosphatidylinositol kinase related protein,
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000468000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000398800 ⚠
cullin-like protein-like protein
— OG7
LAEL147_000635700 ⚠
RNA guanylyltransferase, putative
— OG7
LAEL147_000157100 ⚠
adaptin-related protein-like protein
— OG7
LAEL147_000077800 ⚠
SpoU rRNA Methylase family, putative
— OG7
LAEL147_000636100 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000203700 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LAEL147_000168300 ⚠
vacuolar ATP synthase subunit, putative
— OG7
LAEL147_000659300 ⚠
exosome-associated protein 2, putative
— OG7
LAEL147_000653600 ⚠
ATP binding protein-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.