LAEL147_000524000

guanine deaminase, putative
Leishmania aethiopica L147 OG6: OG6_100650 OG7: OG7_0004147 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000749600 ⚠
pyruvate kinase
— Both
LAEL147_000425500 ⚠
hypothetical protein
— OG7
LAEL147_000425400 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000697300 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000168400
glucose-6-phosphate isomerase
— Both
LAEL147_000474200 ⚠
trypanothione synthetase, putative
— Both
LAEL147_000536200 ⚠
fumarate hydratase, putative
— Both
LAEL147_000376600 ⚠
fumarate hydratase, putative
— Both
LAEL147_000749500 ⚠
pyruvate kinase
— Both
LAEL147_000696900 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000357000 ⚠
acetyl-CoA synthetase, putative
— Both
LAEL147_000361400 ⚠
acetyl-CoA synthetase, putative
— Both
LAEL147_000438100 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000511500 ⚠
Hsp70 protein, putative
— Both
LAEL147_000512000 ⚠
heat-shock protein hsp70, putative
— OG6
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000543800 ⚠
3',5'-cyclic nucleotide phosphodiesterase, pu
— OG7
LAEL147_000869600 ⚠
aminopeptidase P1, putative
— OG7
LAEL147_000799400 ⚠
Hsp70 protein, putative
— OG7
LAEL147_000025300 ⚠
HSP70-like protein
— OG7
LAEL147_000271700 ⚠
heat shock protein 110, putative
— OG7
LAEL147_000434600 ⚠
heat shock 70 protein-like protein
— OG7
LAEL147_000428700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LAEL147_000268900 ⚠
cAMP phosphodiesterase A, putative
— OG7
LAEL147_000541300 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAEL147_000011300 ⚠
S-adenosylmethionine synthetase
— Both
LAEL147_000024100 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LAEL147_000252200 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LAEL147_000808700 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LAEL147_000534000 ⚠
paraflagellar rod protein 1D, putative
— OG7
LAEL147_000534100 ⚠
paraflagellar rod protein 1D, putative
— OG7
LAEL147_000356100 ⚠
trypanothione synthetase, putative
— OG7
LAEL147_000425300 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000433800
aspartate--ammonia ligase, putative
— Both
LAEL147_000038100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LAEL147_000657200
glucosamine-6-phosphate isomerase, putative
— Both
LAEL147_000381400 ⚠
malic enzyme, putative
— Both
LAEL147_000381500 ⚠
malic enzyme, putative
— Both
LAEL147_000062900
trypanothione reductase
— Both
LAEL147_000464400
isovaleryl-coA dehydrogenase, putative
— Both
LAEL147_000474000 ⚠
paraflagellar rod protein-like protein
— Both
LAEL147_000773800 ⚠
aminopeptidase P, putative
— Both
LAEL147_000223100 ⚠
cAMP specific phosphodiesterase, putative
— Both
LAEL147_000737400
aldose 1-epimerase-like protein
— Both
LAEL147_000848300 ⚠
cysteine synthase
— Both
LAEL147_000244000 ⚠
cystathionine beta-synthase
— OG6
LAEL147_000147000
seryl-tRNA synthetase, putative
— Both
LAEL147_000578100 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LAEL147_000578000 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.