LAEL147_000464400

isovaleryl-coA dehydrogenase, putative
Leishmania aethiopica L147 OG6: OG6_102105 OG7: OG7_0001034 45 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 45 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000717000 ⚠
inositol 5-phosphatase-like protein
— OG7
LAEL147_000191200 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LAEL147_000219400 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000024000 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LAEL147_000799800 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— Both
LAEL147_000018300 ⚠
S-adenosylmethionine synthetase
— Both
LAEL147_000011300 ⚠
S-adenosylmethionine synthetase
— Both
LAEL147_000826500
aldehyde dehydrogenase, putative
— Both
LAEL147_000703200
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LAEL147_000749600 ⚠
pyruvate kinase
— Both
LAEL147_000749500 ⚠
pyruvate kinase
— Both
LAEL147_000168400
glucose-6-phosphate isomerase
— Both
LAEL147_000350900 ⚠
peroxidoxin
— Both
LAEL147_000382000 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LAEL147_000218600
Rad9, putative
— OG7
LAEL147_000819600 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LAEL147_000794500 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LAEL147_000220100 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LAEL147_000833700 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
LAEL147_000578000 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LAEL147_000578100 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LAEL147_000581100 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LAEL147_000024100 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LAEL147_000426300
pyridoxal phosphate containing glycine decarb
— Both
LAEL147_000076200
glutamine synthetase, putative
— Both
LAEL147_000038100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LAEL147_000016300 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LAEL147_000023800 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LAEL147_000274200 ⚠
nonspecific nucleoside hydrolase
— Both
LAEL147_000157200
pyruvate phosphate dikinase, putative
— Both
LAEL147_000351600
GDP-mannose pyrophosphorylase
— Both
LAEL147_000657200
glucosamine-6-phosphate isomerase, putative
— Both
LAEL147_000023900 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LAEL147_000737400
aldose 1-epimerase-like protein
— Both
LAEL147_000730400
hypothetical protein, conserved
— Both
LAEL147_000219300 ⚠
AhpC/TSA family/C-terminal domain of 1-Cys pe
— Both
LAEL147_000691700 ⚠
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
LAEL147_000219200 ⚠
C-terminal domain of 1-Cys peroxiredoxin, put
— Both
LAEL147_000184200
adenylosuccinate synthetase, putative
— Both
LAEL147_000396500
transketolase
— Both
LAEL147_000023600 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LAEL147_000566700 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LAEL147_000524000
guanine deaminase, putative
— Both
LAEL147_000566600 ⚠
succinyl-coa:3-ketoacid-coenzyme a transferas
— Both
LAEL147_000222700 ⚠
glutaminyl-tRNA synthetase, putative
— Both
Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.