LAEL147_000062900

trypanothione reductase
Leishmania aethiopica L147 OG6: OG6_101659 OG7: OG7_0001626 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000738500 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LAEL147_000597200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000561600 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000689500 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000170700 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LAEL147_000201100
Sodium/hydrogen exchanger family, putative
— Both
LAEL147_000728800 ⚠
ATP-dependent DNA helicase, putative
— Both
LAEL147_000807600 ⚠
stress-inducible protein STI1 homolog
— OG6
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000704100 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— Both
LAEL147_000703900 ⚠
malate dehydrogenase
— Both
LAEL147_000299300
cytidine triphosphate synthase, putative
— Both
LAEL147_000597400 ⚠
Peptidase family M20/M25/M40, putative
— Both
LAEL147_000703800 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000704000 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000282400 ⚠
glycosomal malate dehydrogenase
— OG7
LAEL147_000027000 ⚠
hypothetical protein
— OG7
LAEL147_000884300 ⚠
prolyl oligopeptidase, putative
— OG7
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000583000 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000869600 ⚠
aminopeptidase P1, putative
— OG7
LAEL147_000172000 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LAEL147_000428600 ⚠
aminopeptidase-like protein
— OG7
LAEL147_000536200 ⚠
fumarate hydratase, putative
— Both
LAEL147_000556700 ⚠
conserved hypothetical protein, putative
— Both
LAEL147_000539300 ⚠
aminopeptidase, putative
— Both
LAEL147_000782100
glycerol kinase, glycosomal, putative
— Both
LAEL147_000679800
glutamine aminotransferase, putative
— Both
LAEL147_000067200
methylthioadenosine phosphorylase, putative
— Both
LAEL147_000784800
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LAEL147_000354000
pteridine reductase 1
— Both
LAEL147_000448800
kynureninase, putative
— Both
LAEL147_000580500
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
LAEL147_000376600 ⚠
fumarate hydratase, putative
— Both
LAEL147_000773800 ⚠
aminopeptidase P, putative
— Both
LAEL147_000537800 ⚠
conserved hypothetical protein, putative
— Both
LAEL147_000653300
nucleoside diphosphate kinase b
— Both
LAEL147_000524000
guanine deaminase, putative
— Both
LAEL147_000204000
enolase
— Both
LAEL147_000018300 ⚠
S-adenosylmethionine synthetase
— Both
LAEL147_000011300 ⚠
S-adenosylmethionine synthetase
— Both
LAEL147_000198800
hypothetical protein
— OG6
LAEL147_000075300 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LAEL147_000311000 ⚠
hypothetical protein
— Both
LAEL147_000075700 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LAEL147_000597300 ⚠
hypothetical protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.