LAEL147_000704100

lactate/malate dehydrogenase, alpha/beta C-terminal domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_101212 OG7: OG7_0004751 71 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 71 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000052100 ⚠
spermidine synthase
— Both
LAEL147_000697300 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000006300 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LAEL147_000425500 ⚠
hypothetical protein
— OG7
LAEL147_000462200 ⚠
reductase, putative
— OG7
LAEL147_000182800 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LAEL147_000576300 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LAEL147_000785800 ⚠
Replication factor A protein 3, putative
— OG7
LAEL147_000425400 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000696900 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000201100 ⚠
Sodium/hydrogen exchanger family, putative
— Both
LAEL147_000170700 ⚠
N-acyl-L-amino acid amidohydrolase
— Both
LAEL147_000561600 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000597200 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LAEL147_000597400 ⚠
Peptidase family M20/M25/M40, putative
— Both
LAEL147_000597300 ⚠
hypothetical protein
— Both
LAEL147_000075700 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LAEL147_000062900 ⚠
trypanothione reductase
— Both
LAEL147_000178900 ⚠
Metallopeptidase family M24, putative
— OG7
LAEL147_000517600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000212800 ⚠
ecotin, putative
— OG7
LAEL147_000210800 ⚠
ecotin, putative
— OG7
LAEL147_000349400 ⚠
ser/thr protein phosphatase, putative
— OG7
LAEL147_000011500 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LAEL147_000753200 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LAEL147_000498400 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LAEL147_000857900 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LAEL147_000075300 ⚠
serine peptidase, clan SC, family S9A-like pr
— Both
LAEL147_000369600 ⚠
aminoacyclase, putative
— OG7
LAEL147_000884300 ⚠
prolyl oligopeptidase, putative
— OG7
LAEL147_000027000 ⚠
hypothetical protein
— OG7
LAEL147_000738500 ⚠
ruvb-like 1 DNA helicase, putative
— OG7
LAEL147_000356100 ⚠
trypanothione synthetase, putative
— OG7
LAEL147_000646200 ⚠
cytochrome-b5 reductase, putative
— OG7
LAEL147_000442800 ⚠
cytochrome c oxidase subunit V, putative
— OG7
LAEL147_000425300 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000560200 ⚠
pyridoxal kinase, putative
— Both
LAEL147_000545100 ⚠
inosine-adenosine-guanosine-nucleoside hydrol
— Both
LAEL147_000422500 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LAEL147_000829900 ⚠
TCP-1/cpn60 chaperonin family, putative
— Both
LAEL147_000382300 ⚠
triosephosphate isomerase
— Both
LAEL147_000008100 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LAEL147_000640800 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LAEL147_000422400 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LAEL147_000193600 ⚠
threonine synthase, putative
— Both
LAEL147_000208000 ⚠
cytochrome-b5 reductase, putative
— Both
LAEL147_000474200 ⚠
trypanothione synthetase, putative
— Both
LAEL147_000556700 ⚠
conserved hypothetical protein, putative
— Both
LAEL147_000537800 ⚠
conserved hypothetical protein, putative
— Both
LAEL147_000212900 ⚠
ecotin, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.