LAEL147_000422500

succinyl-CoA synthetase alpha subunit, putative
Leishmania aethiopica L147 OG6: OG6_100834 OG7: OG7_0005210 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000841300 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— +2 more Both
LAEL147_000646200 ⚠
cytochrome-b5 reductase, putative
— OG7
LAEL147_000721400 ⚠
pyroglutamyl-peptidase I (C15 family)
— Both
LAEL147_000132700 ⚠
mitogen-activated protein kinase, putative
— OG6
LAEL147_000506100 ⚠
hd phosphohydrolase family protein
— Both
LAEL147_000853000 ⚠
hs1vu complex proteolytic subunit-like, threo
— Both
LAEL147_000742100 ⚠
phosphomannomutase-like protein
— Both
LAEL147_000621500 ⚠
N-myristoyl transferase, putative
— Both
LAEL147_000502900 ⚠
ribose 5-phosphate isomerase, putative
— Both
LAEL147_000083900 ⚠
deoxyribose-phosphate aldolase, putative
— Both
LAEL147_000703800 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000704000 ⚠
malate dehydrogenase, putative
— OG7
LAEL147_000282400 ⚠
glycosomal malate dehydrogenase
— OG7
LAEL147_000182800 ⚠
NADH-cytochrome b5 reductase, putative
— OG7
LAEL147_000462200 ⚠
reductase, putative
— OG7
LAEL147_000006300 ⚠
NADH-cytochrome b5 reductase-like protein
— OG7
LAEL147_000210200 ⚠
sterol carrier protein, putative
— OG7
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000752700 ⚠
serine palmitoyltransferase, putative
— OG7
LAEL147_000741600 ⚠
serine palmitoyltransferase-like protein
— OG7
LAEL147_000660700 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000660800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000337300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LAEL147_000291200 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LAEL147_000496200 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LAEL147_000496300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000496700 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000496500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000496400 ⚠
hypothetical protein
— OG7
LAEL147_000749000 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LAEL147_000303400 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LAEL147_000800000 ⚠
cyclophilin 40
— OG6
LAEL147_000381400 ⚠
malic enzyme, putative
— Both
LAEL147_000361200 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LAEL147_000613000 ⚠
uridine kinase-like protein
— Both
LAEL147_000397000 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LAEL147_000008100 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LAEL147_000208000 ⚠
cytochrome-b5 reductase, putative
— Both
LAEL147_000008200 ⚠
NADH-cytochrome b5 reductase, putative
— Both
LAEL147_000133800 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LAEL147_000427000 ⚠
adenine phosphoribosyltransferase
— Both
LAEL147_000714100 ⚠
uracil phosphoribosyltransferase, putative
— Both
LAEL147_000858400 ⚠
Protein of unknown function (DUF2870), putati
— Both
LAEL147_000749600 ⚠
pyruvate kinase
— Both
LAEL147_000749500 ⚠
pyruvate kinase
— Both
LAEL147_000657700 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
LAEL147_000550300 ⚠
phosphatase 2C, putative
— OG6
LAEL147_000335400 ⚠
glutamine amidotransferase, putative
— Both
LAEL147_000660900 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— Both
LAEL147_000704100 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.