LAEL147_000749000

1,2-Dihydroxy-3-keto-5-methylthiopentene dioxygenase, putative
Leishmania aethiopica L147 OG6: OG6_102069 OG7: OG7_0005923 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000427000 ⚠
adenine phosphoribosyltransferase
— Both
LAEL147_000741600 ⚠
serine palmitoyltransferase-like protein
— OG7
LAEL147_000469700 ⚠
Snf7, putative
— OG7
LAEL147_000473300 ⚠
casein kinase I-like protein
— OG7
LAEL147_000209000 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LAEL147_000208800 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LAEL147_000875400 ⚠
rab-like GTPase activating protein, putative
— OG7
LAEL147_000698900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000583700 ⚠
casein kinase 1 isoform 2, putative
— OG7
LAEL147_000759900 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LAEL147_000058700 ⚠
casein kinase I, putative
— OG7
LAEL147_000416600 ⚠
casein kinase I, putative
— OG7
LAEL147_000587600 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000752700 ⚠
serine palmitoyltransferase, putative
— OG7
LAEL147_000455600 ⚠
WW domain/Zinc finger C-x8-C-x5-C-x3-H type (
— OG7
LAEL147_000645400 ⚠
heat shock protein Hsp20, putative
— OG7
LAEL147_000649700 ⚠
superoxide dismutase, putative
— OG7
LAEL147_000640600 ⚠
iron superoxide dismutase, putative
— OG7
LAEL147_000103900 ⚠
iron superoxide dismutase
— OG7
LAEL147_000355100 ⚠
NADP-dependent alcohol dehydrogenase, putativ
— OG7
LAEL147_000161900 ⚠
PITH domain containing protein, putative
— OG7
LAEL147_000422400 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LAEL147_000621500 ⚠
N-myristoyl transferase, putative
— OG7
LAEL147_000422500 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LAEL147_000764500 ⚠
arginase
— OG7
LAEL147_000170900 ⚠
n-ethylmaleimide reductase-like protein
— OG7
LAEL147_000170800 ⚠
NADH:flavin oxidoreductase/NADH oxidase, puta
— OG7
LAEL147_000601200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000435700 ⚠
hypothetical protein, conserved
— Both
LAEL147_000717400 ⚠
PTP1-interacting protein, 39 kDa, putative
— Both
LAEL147_000849200 ⚠
nudix hydrolase-like protein
— Both
LAEL147_000876400 ⚠
NUP50 (Nucleoporin 50 kDa), putative
— Both
LAEL147_000630800 ⚠
Alpha/beta hydrolase family, putative
— Both
LAEL147_000846800 ⚠
SNF7-like protein
— Both
LAEL147_000574100 ⚠
RNA-binding protein, putative
— OG6
LAEL147_000659600 ⚠
hypothetical protein, conserved
— Both
LAEL147_000759700 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— Both
LAEL147_000875300 ⚠
disgorgin, putative
— Both
LAEL147_000831800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000378500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000733500 ⚠
protein kinase, putative
— OG7
LAEL147_000759600 ⚠
casein kinase, putative
— Both
LAEL147_000698700 ⚠
hypothetical protein, conserved
— Both
LAEL147_000710700 ⚠
Uncharacterized conserved protein (DUF2039),
— Both
LAEL147_000373300 ⚠
Nucleoside 2-deoxyribosyltransferase, putativ
— Both
LAEL147_000570900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000139600 ⚠
hypothetical protein, conserved
— Both
LAEL147_000079400 ⚠
hypothetical protein, conserved
— Both
LAEL147_000396500 ⚠
transketolase
— OG7
LAEL147_000584300 ⚠
Zinc finger CCCH domain-containing protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.