LAEL147_000161900

PITH domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_102988 OG7: OG7_0006444 191 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 191 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000496200 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LAEL147_000496300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000496700 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000496400 ⚠
hypothetical protein
— Both
LAEL147_000496600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— +1 more Both
LAEL147_000496100 ⚠
hypothetical protein
— +1 more Both
LAEL147_000496500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— Both
LAEL147_000876600
Sucrase/ferredoxin-like, putative
— Both
LAEL147_000103900 ⚠
iron superoxide dismutase
— Both
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
LAEL147_000108900
hypothetical protein, conserved
— OG7
LAEL147_000660800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000660700 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000010200 ⚠
biotin/lipoate protein ligase-like protein
— Both
LAEL147_000522700 ⚠
U-box domain protein, putative
— Both
LAEL147_000812900 ⚠
protein phosphatase 2C-like protein
— OG6
LAEL147_000097700 ⚠
serine/threonine kinase, putative
— Both
LAEL147_000264500 ⚠
serine/threonine kinase-like protein, putativ
— Both
LAEL147_000518100
UBX domain-containing protein
— Both
LAEL147_000198800
hypothetical protein
— OG6
LAEL147_000649700 ⚠
superoxide dismutase, putative
— Both
LAEL147_000807600 ⚠
stress-inducible protein STI1 homolog
— OG6
LAEL147_000813400 ⚠
Elongation factor G1, mitochondrial, putative
— Both
LAEL147_000105900
hypothetical protein, conserved
— Both
LAEL147_000204300
YjeF family N-terminal domain/YjeF family C-t
— Both
LAEL147_000454100
6-phosphogluconolactonase
— Both
LAEL147_000721400
pyroglutamyl-peptidase I (C15 family)
— Both
LAEL147_000816700
eukaryotic translation initiation factor 6 (e
— Both
LAEL147_000229800
dihydroorotase, putative
— Both
LAEL147_000136200
mitogen-activated protein kinase 3, putative
— OG6
LAEL147_000596700 ⚠
biotin/lipoate protein ligase-like protein
— Both
LAEL147_000652900 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000062600 ⚠
monothiol glutaredoxin, putative
— Both
LAEL147_000133800
isocitrate dehydrogenase [NADP], mitochondria
— Both
LAEL147_000640600 ⚠
iron superoxide dismutase, putative
— Both
LAEL147_000665200
hypothetical protein, conserved
— Both
LAEL147_000132700
mitogen-activated protein kinase, putative
— OG6
LAEL147_000762200 ⚠
monothiol glutaredoxin, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.