LAEL147_000660800

3-hydroxyisobutyryl-coenzyme a hydrolase-like protein
Leishmania aethiopica L147 OG6: OG6_138999 OG7: OG7_0000750 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000231500 ⚠
transaldolase, putative
— OG7
LAEL147_000496100 ⚠
hypothetical protein
— OG7
LAEL147_000011500 ⚠
eukaryotic initiation factor 4a, putative
— OG7
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000437800 ⚠
aldo/keto reductase, putative
— OG7
LAEL147_000479900 ⚠
aldo-keto reductase-like protein
— OG7
LAEL147_000672700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000371900 ⚠
alanine racemase, putative
— OG7
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— OG7
LAEL147_000744400 ⚠
adaptor gamma-1 chain, putative
— OG7
LAEL147_000087400 ⚠
alpha-adaptin-like protein
— OG7
LAEL147_000450200 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
LAEL147_000631400 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG7
LAEL147_000630800 ⚠
Alpha/beta hydrolase family, putative
— OG7
LAEL147_000587600 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000638100 ⚠
phosphomannose isomerase
— OG7
LAEL147_000740000 ⚠
adenosine kinase-like protein
— OG7
LAEL147_000422400 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LAEL147_000556200 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LAEL147_000556100 ⚠
adenosine kinase, putative
— OG7
LAEL147_000422500 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LAEL147_000556300 ⚠
adenosine kinase-like protein
— OG7
LAEL147_000321400 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— OG7
LAEL147_000321500 ⚠
xanthine phosphoribosyltransferase
— OG7
LAEL147_000548200 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LAEL147_000410500 ⚠
dehydrogenase-like protein
— OG7
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— OG7
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— OG7
LAEL147_000337300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LAEL147_000291200 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LAEL147_000528800 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LAEL147_000738200 ⚠
amidinotransferase, putative
— OG7
LAEL147_000646800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000742100 ⚠
phosphomannomutase-like protein
— OG7
LAEL147_000496600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LAEL147_000616800 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LAEL147_000237500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000675200 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LAEL147_000841300 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— OG7
LAEL147_000043600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000603400 ⚠
diphthine synthase-like protein
— OG7
LAEL147_000377200 ⚠
aspartate aminotransferase, putative
— OG7
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— OG7
LAEL147_000021000 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LAEL147_000883100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LAEL147_000493500 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000696700 ⚠
transcription elongation factor-like protein
— OG7
LAEL147_000375500 ⚠
transcription elongation factor, putative
— OG7
LAEL147_000428800 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LAEL147_000337700 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.