LAEL147_000548200

2-hydroxy-3-oxopropionate reductase, putative
Leishmania aethiopica L147 OG6: OG6_101839 OG7: OG7_0002731 215 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 215 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000179400 ⚠
ubiquitin-like protein
— Both
LAEL147_000813100 ⚠
ubiquitin-like protein, putative
— OG7
LAEL147_000462100 ⚠
UBA/TS-N domain containing protein, putative
— Both
LAEL147_000574700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000332800 ⚠
RNA polymerase II, putative
— OG7
LAEL147_000007800 ⚠
serine/threonine protein kinase sos2, putativ
— OG7
LAEL147_000503400 ⚠
protein kinase, putative
— OG7
LAEL147_000337300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LAEL147_000660700 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000744400 ⚠
adaptor gamma-1 chain, putative
— OG7
LAEL147_000311900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000845000 ⚠
Enoyl-CoA hydratase/isomerase family/2-enoyl-
— OG7
LAEL147_000036400 ⚠
Met-10+ like-protein, putative
— OG7
LAEL147_000331500 ⚠
mitochondrial RNA binding complex 1 subunit,
— OG7
LAEL147_000479900 ⚠
aldo-keto reductase-like protein
— OG7
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000474500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000809200 ⚠
small GTP-binding protein domain containing p
— OG7
LAEL147_000809100 ⚠
elongation factor 2
— OG7
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000006700 ⚠
elongation factor 2
— OG7
LAEL147_000108900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000038000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000226100 ⚠
50S ribosomal protein L17, putative
— OG7
LAEL147_000111000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000449100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000786300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000046800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000210700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000179900 ⚠
protein kinase, putative
— Both
LAEL147_000200400 ⚠
glutathione synthetase, putative
— Both
LAEL147_000421800 ⚠
elongation factor 2-like protein
— Both
LAEL147_000377200 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000496600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LAEL147_000496100 ⚠
hypothetical protein
— Both
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000493500 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000337400 ⚠
SEP domain containing protein, putative
— Both
LAEL147_000371900 ⚠
alanine racemase, putative
— Both
LAEL147_000493900 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAEL147_000298600 ⚠
hypothetical protein, conserved
— Both
LAEL147_000227600 ⚠
Met-10+ like-protein, putative
— Both
LAEL147_000845800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000174500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000067800 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.