LAEL147_000462100

UBA/TS-N domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_129093 OG7: OG7_0004831 163 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 163 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000548200 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LAEL147_000410500 ⚠
dehydrogenase-like protein
— OG7
LAEL147_000359700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LAEL147_000264500 ⚠
serine/threonine kinase-like protein, putativ
— Both
LAEL147_000132700
mitogen-activated protein kinase, putative
— OG6
LAEL147_000267800 ⚠
UDP-glucose pyrophosphorylase
— Both
LAEL147_000414200 ⚠
TAP42-like family, putative
— Both
LAEL147_000098500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000665200 ⚠
hypothetical protein, conserved
— Both
LAEL147_000413300 ⚠
NPL4 family, putative
— Both
LAEL147_000639200 ⚠
protein phosphatase 2C, putative
— OG6
LAEL147_000596700 ⚠
biotin/lipoate protein ligase-like protein
— Both
LAEL147_000749500 ⚠
pyruvate kinase
— Both
LAEL147_000133800 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000318600 ⚠
phosphoglucomutase, putative
— Both
LAEL147_000311100 ⚠
pentatricopeptide repeat domain containing pr
— Both
LAEL147_000097700 ⚠
serine/threonine kinase, putative
— Both
LAEL147_000812900 ⚠
protein phosphatase 2C-like protein
— OG6
LAEL147_000522700 ⚠
U-box domain protein, putative
— Both
LAEL147_000010200 ⚠
biotin/lipoate protein ligase-like protein
— Both
LAEL147_000797000 ⚠
CS domain containing protein, putative
— Both
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— Both
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— Both
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000692500 ⚠
diphthamide biosynthesis enzyme Dph1/Dph2 dom
— OG7
LAEL147_000660700 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000660800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000108900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000479900 ⚠
aldo-keto reductase-like protein
— OG7
LAEL147_000744400 ⚠
adaptor gamma-1 chain, putative
— OG7
LAEL147_000087400 ⚠
alpha-adaptin-like protein
— OG7
LAEL147_000157200 ⚠
pyruvate phosphate dikinase, putative
— OG7
LAEL147_000178900 ⚠
Metallopeptidase family M24, putative
— OG7
LAEL147_000276700 ⚠
metallo-peptidase, Clan MG, Family M24
— OG7
LAEL147_000200400 ⚠
glutathione synthetase, putative
— OG7
LAEL147_000756700 ⚠
proteasome activator protein pa26, putative
— OG7
LAEL147_000179900 ⚠
protein kinase, putative
— OG7
LAEL147_000332800 ⚠
RNA polymerase II, putative
— OG7
LAEL147_000684500 ⚠
protein kinase, putative
— OG7
LAEL147_000536900 ⚠
serine/threonine protein kinase, putative
— OG7
LAEL147_000816800 ⚠
SNF1-related protein kinases, putative
— OG7
LAEL147_000508800 ⚠
eukaryotic translation initiation factor 4e,
— OG7
LAEL147_000503400 ⚠
protein kinase, putative
— OG7
LAEL147_000334000 ⚠
beta tubulin
— OG7
LAEL147_000311900 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.