LAEL147_000428800

C-1-tetrahydrofolate synthase, cytoplasmic, putative
Leishmania aethiopica L147 OG6: OG6_100216 OG7: OG7_0002739 226 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 226 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000021100 ⚠
cyclophilin 12, putative
— OG6
LAEL147_000481800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000348700 ⚠
alanyl-tRNA synthetase, putative
— OG6
LAEL147_000067600 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000479100 ⚠
GTP binding protein, putative
— Both
LAEL147_000224700 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAEL147_000337400 ⚠
SEP domain containing protein, putative
— Both
LAEL147_000371900 ⚠
alanine racemase, putative
— Both
LAEL147_000493900 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LAEL147_000493500 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000345100 ⚠
translation initiation factor IF-2, putative
— OG6
LAEL147_000377200 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000346000 ⚠
translation initiation factor IF-2, putative
— OG6
LAEL147_000258200 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
LAEL147_000337200 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000082600 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG6
LAEL147_000014500 ⚠
calreticulin, putative
— OG6
LAEL147_000231500 ⚠
transaldolase, putative
— Both
LAEL147_000007000 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000335400 ⚠
glutamine amidotransferase, putative
— Both
LAEL147_000435600 ⚠
Glucosidase II beta subunit-like/Glucosidase
— OG6
LAEL147_000183200 ⚠
leucyl-tRNA synthetase, putative
— OG6
LAEL147_000583000 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000316800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000074300 ⚠
5'-3' exonuclease, putative
— Both
LAEL147_000283400 ⚠
ABC transport system ATP-binding protein, put
— OG6
LAEL147_000305200 ⚠
Pre-mRNA-splicing factor 38, putative
— OG6
LAEL147_000778100 ⚠
acyl-CoA dehydrogenase, putative
— OG6
LAEL147_000749500 ⚠
pyruvate kinase
— Both
LAEL147_000640600 ⚠
iron superoxide dismutase, putative
— Both
LAEL147_000425700 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000603400 ⚠
diphthine synthase-like protein
— Both
LAEL147_000760000 ⚠
protein kinase, putative
— OG6
LAEL147_000828900 ⚠
phosphomannomutase, putative
— OG6
LAEL147_000133800 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LAEL147_000062600 ⚠
monothiol glutaredoxin, putative
— Both
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000450200 ⚠
Zn-finger in Ran binding protein and others/S
— Both
LAEL147_000528800 ⚠
carnitine/choline acetyltransferase, putative
— Both
LAEL147_000401300 ⚠
cleavage and polyadenylation specificity fact
— OG6
LAEL147_000631400 ⚠
ubiquitin-conjugating enzyme protein, putativ
— Both
LAEL147_000675200 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LAEL147_000812900 ⚠
protein phosphatase 2C-like protein
— OG6
LAEL147_000010200 ⚠
biotin/lipoate protein ligase-like protein
— Both
LAEL147_000259100 ⚠
alpha glucosidase II subunit, putative
— OG6
LAEL147_000522700 ⚠
U-box domain protein, putative
— Both
LAEL147_000797000 ⚠
CS domain containing protein, putative
— Both
LAEL147_000742100 ⚠
phosphomannomutase-like protein
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.