LAEL147_000021100

cyclophilin 12, putative
Leishmania aethiopica L147 OG6: OG6_109053 OG7: OG7_0000556 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000749600 ⚠
pyruvate kinase
— OG6
LAEL147_000646800
hypothetical protein, conserved
— OG6
LAEL147_000041400
quinone oxidoreductase, putative
— OG6
LAEL147_000672700
WD domain, G-beta repeat, putative
— OG6
LAEL147_000858400
Protein of unknown function (DUF2870), putati
— OG6
LAEL147_000414200
TAP42-like family, putative
— OG6
LAEL147_000267800
UDP-glucose pyrophosphorylase
— OG6
LAEL147_000132700
mitogen-activated protein kinase, putative
— OG6
LAEL147_000660900
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— OG6
LAEL147_000264500 ⚠
serine/threonine kinase-like protein, putativ
— OG6
LAEL147_000793800 ⚠
Protein of unknown function (DUF2009), putati
— OG6
LAEL147_000229800
dihydroorotase, putative
— OG6
LAEL147_000462100
UBA/TS-N domain containing protein, putative
— OG6
LAEL147_000310300 ⚠
SNAP protein, putative
— OG6
LAEL147_000621500
N-myristoyl transferase, putative
— OG6
LAEL147_000260400
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LAEL147_000816700
eukaryotic translation initiation factor 6 (e
— OG6
LAEL147_000721400
pyroglutamyl-peptidase I (C15 family)
— OG6
LAEL147_000630800
Alpha/beta hydrolase family, putative
— OG6
LAEL147_000454100
6-phosphogluconolactonase
— OG6
LAEL147_000204300
YjeF family N-terminal domain/YjeF family C-t
— OG6
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— OG6
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— OG6
LAEL147_000421100
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG6
LAEL147_000105900
hypothetical protein, conserved
— OG6
LAEL147_000450200
Zn-finger in Ran binding protein and others/S
— OG6
LAEL147_000742100
phosphomannomutase-like protein
— OG6
LAEL147_000675200
nicotinate phosphoribosyltransferase, putativ
— OG6
LAEL147_000797000 ⚠
CS domain containing protein, putative
— OG6
LAEL147_000010200 ⚠
biotin/lipoate protein ligase-like protein
— OG6
LAEL147_000494900
hypothetical protein, conserved
— OG6
LAEL147_000522700
U-box domain protein, putative
— OG6
LAEL147_000812900 ⚠
protein phosphatase 2C-like protein
— OG6
LAEL147_000097700 ⚠
serine/threonine kinase, putative
— OG6
LAEL147_000318600
phosphoglucomutase, putative
— OG6
LAEL147_000631400
ubiquitin-conjugating enzyme protein, putativ
— OG6
LAEL147_000528800
carnitine/choline acetyltransferase, putative
— OG6
LAEL147_000813400
Elongation factor G1, mitochondrial, putative
— OG6
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000133800
isocitrate dehydrogenase [NADP], mitochondria
— OG6
LAEL147_000749500 ⚠
pyruvate kinase
— OG6
LAEL147_000445200
deoxyhypusine hydroxylase, putative
— OG6
LAEL147_000643300 ⚠
cytidyltransferase-like domain containing pro
— OG6
LAEL147_000877300
small G-protein, putative
— OG6
LAEL147_000596700 ⚠
biotin/lipoate protein ligase-like protein
— OG6
LAEL147_000639200 ⚠
protein phosphatase 2C, putative
— OG6
LAEL147_000883100
2,3-bisphosphoglycerate-independent phosphogl
— OG6
LAEL147_000413300
NPL4 family, putative
— OG6
LAEL147_000665200
hypothetical protein, conserved
— OG6
LAEL147_000574000 ⚠
formate--tetrahydrofolate ligase
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.