LAEL147_000631400

ubiquitin-conjugating enzyme protein, putative
Leishmania aethiopica L147 OG6: OG6_101758 OG7: OG7_0003023 139 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 139 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000617500 ⚠
aldehyde reductase, putative
— OG7
LAEL147_000553300
Phosphatidylinositol-specific phospholipase C
— Both
LAEL147_000237500
hypothetical protein, conserved
— Both
LAEL147_000592100
amino acid transporter aATP11, putative
— OG6
LAEL147_000574000 ⚠
formate--tetrahydrofolate ligase
— OG6
LAEL147_000428800 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
LAEL147_000335400
glutamine amidotransferase, putative
— Both
LAEL147_000231500
transaldolase, putative
— Both
LAEL147_000826800 ⚠
exoribonuclease 2, putative
— Both
LAEL147_000074300 ⚠
5'-3' exonuclease, putative
— Both
LAEL147_000646800
hypothetical protein, conserved
— Both
LAEL147_000574100
RNA-binding protein, putative
— OG6
LAEL147_000377200 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000496600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LAEL147_000496100 ⚠
hypothetical protein
— Both
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000261200 ⚠
Dephospho-CoA kinase, putative
— Both
LAEL147_000493500
WD domain, G-beta repeat, putative
— Both
LAEL147_000643300 ⚠
cytidyltransferase-like domain containing pro
— Both
LAEL147_000493900
electron-transfer-flavoprotein, alpha polypep
— Both
LAEL147_000371900 ⚠
alanine racemase, putative
— Both
LAEL147_000337400
SEP domain containing protein, putative
— Both
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAEL147_000742100
phosphomannomutase-like protein
— Both
LAEL147_000587600
ubiquitin hydrolase, putative
— Both
LAEL147_000504200
tRNA threonylcarbamoyl adenosine modification
— Both
LAEL147_000696700 ⚠
transcription elongation factor-like protein
— Both
LAEL147_000434700
hypothetical protein, conserved
— Both
LAEL147_000225900
eukaryotic translation initiation factor 1A,
— Both
LAEL147_000021100
cyclophilin 12, putative
— OG6
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000108900
hypothetical protein, conserved
— OG7
LAEL147_000496300 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LAEL147_000647600 ⚠
Cid1 family poly A polymerase, putative
— OG7
LAEL147_000179400 ⚠
ubiquitin-like protein
— OG7
LAEL147_000313300 ⚠
serine/threonine-protein kinase-like protein
— OG7
LAEL147_000077900 ⚠
U-box domain containing protein, putative
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
LAEL147_000660800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000410500 ⚠
dehydrogenase-like protein
— OG7
LAEL147_000496200 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LAEL147_000254500 ⚠
5'-3' exonuclease, putative
— OG7
LAEL147_000375500 ⚠
transcription elongation factor, putative
— OG7
LAEL147_000337600 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
LAEL147_000337700 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAEL147_000021000 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LAEL147_000496500 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.