LAEL147_000553300

Phosphatidylinositol-specific phospholipase C, X domain/PDZ domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_146793 OG7: OG7_0037550 188 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 188 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000060800
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LAEL147_000045900 ⚠
MORN repeat, putative
— Both
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— Both
LAEL147_000349700
CCR4 associated factor, putative
— Both
LAEL147_000053400
Axonemal dynein light chain, putative
— Both
LAEL147_000282200 ⚠
hypothetical protein
— OG6
LAEL147_000282000 ⚠
kinesin, putative
— OG6
LAEL147_000282100 ⚠
kinesin, putative
— OG6
LAEL147_000546700
MATH domain containing protein, putative
— Both
LAEL147_000377200 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000496600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LAEL147_000496100 ⚠
hypothetical protein
— Both
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000216400
hypothetical protein, conserved
— Both
LAEL147_000493500
WD domain, G-beta repeat, putative
— Both
LAEL147_000371900 ⚠
alanine racemase, putative
— Both
LAEL147_000493900
electron-transfer-flavoprotein, alpha polypep
— Both
LAEL147_000337400
SEP domain containing protein, putative
— Both
LAEL147_000372000 ⚠
Alanine racemase, N-terminal domain containin
— Both
LAEL147_000169100 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LAEL147_000587600
ubiquitin hydrolase, putative
— Both
LAEL147_000619800
hypothetical protein, conserved
— Both
LAEL147_000635500
cleavage and polyadenylation specificity fact
— Both
LAEL147_000818000
intraflagellar transport protein IFT122, puta
— Both
LAEL147_000268800 ⚠
protein kinase A catalytic subunit
— OG6
LAEL147_000624000
hypothetical protein, conserved
— Both
LAEL147_000791600 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LAEL147_000569900
endosomal trafficking protein RME-8, putative
— Both
LAEL147_000553900
CDC16, putative
— Both
LAEL147_000878400 ⚠
ubiquitin-protein ligase, putative
— Both
LAEL147_000623400
hypothetical protein, conserved
— Both
LAEL147_000792100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LAEL147_000504200
tRNA threonylcarbamoyl adenosine modification
— Both
LAEL147_000696700 ⚠
transcription elongation factor-like protein
— Both
LAEL147_000084900
hypothetical protein, conserved
— Both
LAEL147_000019200 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000188700 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000589200 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LAEL147_000174400 ⚠
MCAK-like kinesin, putative
— OG7
LAEL147_000070300 ⚠
MORN repeat, putative
— OG7
LAEL147_000727700 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAEL147_000726600 ⚠
Sec7 domain containing protein, putative
— OG7
LAEL147_000108900
hypothetical protein, conserved
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000660800 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LAEL147_000077900 ⚠
U-box domain containing protein, putative
— OG7
LAEL147_000290300 ⚠
eukaryotic translation initiation factor-like
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.