LAEL147_000169100

TPR repeat/Tetratricopeptide repeat, putative
Leishmania aethiopica L147 OG6: OG6_102790 OG7: OG7_0003813 111 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 111 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000063500 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— Both
LAEL147_000049900 ⚠
anaphase promoting complex, subunit 10-like p
— +2 more Both
LAEL147_000383100 ⚠
hypothetical protein, conserved
— +2 more Both
LAEL147_000553900 ⚠
CDC16, putative
— +2 more Both
LAEL147_000084900 ⚠
hypothetical protein, conserved
— +1 more Both
LAEL147_000567400 ⚠
cyclosome subunit-like protein
— +2 more Both
LAEL147_000743800 ⚠
target of rapamycin kinase (TOR) kinase 3
— OG7
LAEL147_000401300 ⚠
cleavage and polyadenylation specificity fact
— Both
LAEL147_000792100 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LAEL147_000822900 ⚠
N-terminal region of Chorein, a TM vesicle-me
— Both
LAEL147_000663500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LAEL147_000269000 ⚠
Ankyrin repeats (3 copies)/Ankyrin repeat, pu
— Both
LAEL147_000282100 ⚠
kinesin, putative
— OG6
LAEL147_000245800 ⚠
hypothetical protein, conserved
— Both
LAEL147_000070300 ⚠
MORN repeat, putative
— OG7
LAEL147_000727700 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAEL147_000726600 ⚠
Sec7 domain containing protein, putative
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000174700 ⚠
protein kinase A regulatory subunit, putative
— OG7
LAEL147_000306200 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAEL147_000187300 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAEL147_000040500 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000731300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LAEL147_000005500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000051500 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LAEL147_000786500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LAEL147_000777400 ⚠
ankyrin repeat protein, putative
— OG7
LAEL147_000101000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LAEL147_000230300 ⚠
RING-H2 zinc finger containing protein, putat
— OG7
LAEL147_000391000 ⚠
ring-box protein, putative
— OG7
LAEL147_000311800 ⚠
ring-box protein 1, putative
— OG7
LAEL147_000230400 ⚠
RING-H2 zinc finger containing protein, putat
— OG7
LAEL147_000656000 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAEL147_000656100 ⚠
IQ calmodulin-binding motif containing protei
— OG7
LAEL147_000878100 ⚠
target of rapamycin (TOR) kinase 1, putative
— OG7
LAEL147_000718900 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LAEL147_000038600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000063400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LAEL147_000663900 ⚠
cAMP response protein, putative
— OG7
LAEL147_000433000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000038500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000581300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000747500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000304900 ⚠
phosphatidylinositol 3-kinase, putative
— Both
LAEL147_000526700 ⚠
Ankyrin repeats (3 copies), putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.