LAEL147_000663500

SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania aethiopica L147 OG6: OG6_147203 OG7: OG7_0031172 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000651900
proteasome regulatory non-ATP-ase subunit, pu
— Both
LAEL147_000005500 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000718900 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LAEL147_000240600 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000567400
cyclosome subunit-like protein
— Both
LAEL147_000643900
RNA recognition motif. (a.k.a. RRM, RBD, or R
— Both
LAEL147_000251900 ⚠
ATP-dependent RNA helicase, putative
— Both
LAEL147_000515600
proteasome regulatory non-ATPase subunit, put
— Both
LAEL147_000219700 ⚠
Cyclic nucleotide-binding domain containing p
— Both
LAEL147_000164300
proteasome regulatory ATPase subunittcc1l8.3,
— OG6
LAEL147_000667400
WD domain, G-beta repeat, putative
— Both
LAEL147_000624900
19S proteasome non-atpase subunit 8
— Both
LAEL147_000853800 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000286000
proteasome regulatory non-ATP-ase subunit 9,
— Both
LAEL147_000100500
proteasome regulatory non-ATP-ase subunit, pu
— Both
LAEL147_000791500
U5 snRNA-associated splicing factor
— Both
LAEL147_000250500
OSM3-like kinesin, putative
— OG6
LAEL147_000177000 ⚠
ATP-dependent RNA helicase, putative
— Both
LAEL147_000469900
proteasome regulatory non-ATP-ase subunit 3,
— Both
LAEL147_000319900
proteasome regulatory non-ATP-ase subunit 5,
— Both
LAEL147_000857000
proteasome regulatory ATPase subunit
— OG6
LAEL147_000383100
hypothetical protein, conserved
— Both
LAEL147_000169100 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LAEL147_000526700 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000636100 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LAEL147_000749200 ⚠
Cyclic nucleotide-binding domain containing p
— OG7
LAEL147_000369300 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LAEL147_000663900 ⚠
cAMP response protein, putative
— OG7
LAEL147_000731300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LAEL147_000174700 ⚠
protein kinase A regulatory subunit, putative
— OG7
LAEL147_000038600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000038500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000306200 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LAEL147_000737800 ⚠
cleavage and polyadenylation specificity fact
— OG7
LAEL147_000624000
hypothetical protein, conserved
— Both
LAEL147_000581300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000747500 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000665800 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LAEL147_000777400 ⚠
ankyrin repeat protein, putative
— OG7
LAEL147_000051500 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LAEL147_000040500 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LAEL147_000433000 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000721600 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LAEL147_000150200 ⚠
chromatin binding protein, putative
— OG7
LAEL147_000837100 ⚠
cyclin-e binding protein 1-like protein
— OG7
LAEL147_000068800
paraflagellar rod protein, putative
— Both
LAEL147_000051800
Tetratricopeptide repeat/TPR repeat, putative
— Both
LAEL147_000551500
hypothetical protein, conserved
— Both
LAEL147_000199300
kinesin, putative
— OG6
LAEL147_000500300
proteasome regulatory non-ATP-ase subunit 2,
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.