LAEL147_000381400

malic enzyme, putative
Leishmania aethiopica L147 OG6: OG6_100205 OG7: OG7_0002857 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000356100 ⚠
trypanothione synthetase, putative
— OG7
LAEL147_000361400 ⚠
acetyl-CoA synthetase, putative
— Both
LAEL147_000357000 ⚠
acetyl-CoA synthetase, putative
— Both
LAEL147_000619700 ⚠
phosphoglycan beta 1,3 galactosyltransferase
— Both
LAEL147_000619600 ⚠
hypothetical protein
— Both
LAEL147_000564300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LAEL147_000474200 ⚠
trypanothione synthetase, putative
— Both
LAEL147_000883100 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LAEL147_000697300 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000425400 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000425500 ⚠
hypothetical protein
— OG7
LAEL147_000696900 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LAEL147_000425300 ⚠
glutathionylspermidine synthase, putative
— OG7
LAEL147_000169300 ⚠
alanine aminotransferase
— Both
LAEL147_000434600 ⚠
heat shock 70 protein-like protein
— OG7
LAEL147_000152900 ⚠
aminopeptidase, putative
— OG7
LAEL147_000153000 ⚠
aminopeptidase, putative
— OG7
LAEL147_000271700 ⚠
heat shock protein 110, putative
— OG7
LAEL147_000025300 ⚠
HSP70-like protein
— OG7
LAEL147_000799400 ⚠
Hsp70 protein, putative
— OG7
LAEL147_000534100 ⚠
paraflagellar rod protein 1D, putative
— OG7
LAEL147_000534000 ⚠
paraflagellar rod protein 1D, putative
— OG7
LAEL147_000869600 ⚠
aminopeptidase P1, putative
— OG7
LAEL147_000421800 ⚠
elongation factor 2-like protein
— OG7
LAEL147_000644700 ⚠
small nuclear ribonucleoprotein component-lik
— OG7
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LAEL147_000283400 ⚠
ABC transport system ATP-binding protein, put
— OG7
LAEL147_000809200 ⚠
small GTP-binding protein domain containing p
— Both
LAEL147_000422400 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LAEL147_000784800 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LAEL147_000264900 ⚠
citrate synthase, putative
— Both
LAEL147_000422500 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LAEL147_000376600 ⚠
fumarate hydratase, putative
— Both
LAEL147_000536200 ⚠
fumarate hydratase, putative
— Both
LAEL147_000133800 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— +2 more Both
LAEL147_000056400 ⚠
hypothetical protein, conserved
— Both
LAEL147_000204000 ⚠
enolase
— Both
LAEL147_000773800 ⚠
aminopeptidase P, putative
— Both
LAEL147_000474000 ⚠
paraflagellar rod protein-like protein
— Both
LAEL147_000006700 ⚠
elongation factor 2
— Both
LAEL147_000809100 ⚠
elongation factor 2
— Both
LAEL147_000381500 ⚠
malic enzyme, putative
— Both
LAEL147_000263400 ⚠
aconitase, putative
— Both
LAEL147_000694000 ⚠
aminopeptidase, putative
— Both
LAEL147_000784000 ⚠
Peroxin 19
— Both
LAEL147_000511600 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000494700 ⚠
heat-shock protein hsp70, putative
— Both
LAEL147_000244000 ⚠
cystathionine beta-synthase
— OG6
LAEL147_000433800 ⚠
aspartate--ammonia ligase, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.