LAEL147_000784800

6-phosphogluconate dehydrogenase, decarboxylating, putative
Leishmania aethiopica L147 OG6: OG6_100975 OG7: OG7_0005833 27 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 27 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000580500
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
LAEL147_000428600 ⚠
aminopeptidase-like protein
— OG7
LAEL147_000172000 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LAEL147_000210200 ⚠
sterol carrier protein, putative
— OG7
LAEL147_000397000
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LAEL147_000361200 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
LAEL147_000168400
glucose-6-phosphate isomerase
— Both
LAEL147_000653300
nucleoside diphosphate kinase b
— Both
LAEL147_000536200 ⚠
fumarate hydratase, putative
— Both
LAEL147_000376600 ⚠
fumarate hydratase, putative
— Both
LAEL147_000280600
metallo- peptidase, Clan MG, Family M24
— Both
LAEL147_000067200
methylthioadenosine phosphorylase, putative
— Both
LAEL147_000169300
alanine aminotransferase
— Both
LAEL147_000491000
ribonucleoside-diphosphate reductase large ch
— Both
LAEL147_000133800
isocitrate dehydrogenase [NADP], mitochondria
— Both
LAEL147_000539300 ⚠
aminopeptidase, putative
— Both
LAEL147_000062900
trypanothione reductase
— Both
LAEL147_000229400
aspartate carbamoyltransferase, putative
— Both
LAEL147_000263400
aconitase, putative
— Both
LAEL147_000757500 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000377200 ⚠
aspartate aminotransferase, putative
— Both
LAEL147_000204000
enolase
— Both
LAEL147_000050700
adenylosuccinate lyase, putative
— Both
LAEL147_000782100
glycerol kinase, glycosomal, putative
— Both
LAEL147_000381400 ⚠
malic enzyme, putative
— Both
LAEL147_000264900
citrate synthase, putative
— Both
LAEL147_000381500 ⚠
malic enzyme, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.