LAEL147_000204000

enolase

Leishmania aethiopica L147 OG6: OG6_100260 OG7: OG7_0002539 41 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 41 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000797000 ⚠ CS domain containing protein, putative	—	OG6 TCSYLVIO_004545 ↔ TCSYLVIO_005716 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_005716	Both
LAEL147_000719100 ⚠ D-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_004545 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_009589 +2 more	Both
LAEL147_000263400 aconitase, putative	—	OG6 Tb927.10.14000 ↔ Tb927.10.2890 OG7 Tb927.10.14000 ↔ Tb927.10.2890	Both
LAEL147_000062900 trypanothione reductase	—	OG6 Tb927.10.10390 ↔ Tb927.10.2890 OG7 Tb927.10.10390 ↔ Tb927.10.2890	Both
LAEL147_000542700 serine/threonine-protein kinase, putative	—	OG6 TCSYLVIO_004423 ↔ TCSYLVIO_004545	OG6
LAEL147_000396500 transketolase	—	OG6 TCSYLVIO_001301 ↔ TCSYLVIO_004545 OG7 TCSYLVIO_001301 ↔ TCSYLVIO_004545	Both
LAEL147_000275100 ⚠ gamma-glutamylcysteine synthetase, putative	—	OG6 TCSYLVIO_004545 ↔ TCSYLVIO_006303 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_006303	Both
LAEL147_000704700 ⚠ CS domain containing protein, putative	—	OG6 TCSYLVIO_004545 ↔ TCSYLVIO_005716 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_005716	Both
LAEL147_000275200 ⚠ Glutamate-cysteine ligase, putative	—	OG6 TCSYLVIO_004545 ↔ TCSYLVIO_006303 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_006303	Both
LAEL147_000883100 2,3-bisphosphoglycerate-independent phosphogl	—	OG6 TCSYLVIO_004545 ↔ TCSYLVIO_004608 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_004608	Both
LAEL147_000828900 phosphomannomutase, putative	—	OG6 TCSYLVIO_004545 ↔ TCSYLVIO_004975 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_004975	Both
LAEL147_000719000 ⚠ d-isomer specific 2-hydroxyacid dehydrogenase	—	OG6 TCSYLVIO_003910 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_003911 ↔ TCSYLVIO_004545 OG6 TCSYLVIO_004545 ↔ TCSYLVIO_009589 OG7 TCSYLVIO_004545 ↔ TCSYLVIO_009589 +2 more	Both
LAEL147_000169300 alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.10.2890 OG7 Tb927.1.3950 ↔ Tb927.10.2890	Both
LAEL147_000008500 3-mercaptopyruvate sulfurtransferase	—	OG6 TCSYLVIO_001928 ↔ TCSYLVIO_004545 OG7 TCSYLVIO_001928 ↔ TCSYLVIO_004545	Both
LAEL147_000337400 SEP domain containing protein, putative	—	OG6 TCSYLVIO_001163 ↔ TCSYLVIO_004545 OG7 TCSYLVIO_001163 ↔ TCSYLVIO_004545	Both
LAEL147_000299300 cytidine triphosphate synthase, putative	—	OG6 Tb927.1.1240 ↔ Tb927.10.2890 OG7 Tb927.1.1240 ↔ Tb927.10.2890	Both
LAEL147_000421800 ⚠ elongation factor 2-like protein	—	OG7 Tb927.10.2890 ↔ Tb927.10.4560	OG7
LAEL147_000172000 ⚠ puromycin-sensitive aminopeptidase-like prote	—	OG7 Tb927.10.2890 ↔ Tb927.3.4750	OG7
LAEL147_000644700 ⚠ small nuclear ribonucleoprotein component-lik	—	OG7 Tb927.10.2890 ↔ Tb927.10.4560	OG7
LAEL147_000428600 ⚠ aminopeptidase-like protein	—	OG7 Tb927.10.2890 ↔ Tb927.3.4750	OG7
LAEL147_000210200 ⚠ sterol carrier protein, putative	—	OG7 Tb927.10.2890 ↔ Tb927.8.2540	OG7
LAEL147_000006700 ⚠ elongation factor 2	—	OG6 Tb927.10.2890 ↔ Tb927.10.4560 OG7 Tb927.10.2890 ↔ Tb927.10.4560	Both
LAEL147_000361200 ⚠ 3-ketoacyl-CoA thiolase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.8.2540 OG7 Tb927.10.2890 ↔ Tb927.8.2540	Both
LAEL147_000381500 ⚠ malic enzyme, putative	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
LAEL147_000539300 ⚠ aminopeptidase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.3.4750 OG7 Tb927.10.2890 ↔ Tb927.3.4750	Both
LAEL147_000782100 glycerol kinase, glycosomal, putative	—	OG6 Tb927.10.2890 ↔ Tb927.9.12570 OG7 Tb927.10.2890 ↔ Tb927.9.12570	Both
LAEL147_000397000 3-hydroxy-3-methylglutaryl-CoA synthase, puta	—	OG6 Tb927.10.2890 ↔ Tb927.8.6110 OG7 Tb927.10.2890 ↔ Tb927.8.6110	Both
LAEL147_000067200 methylthioadenosine phosphorylase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.7.7040 OG7 Tb927.10.2890 ↔ Tb927.7.7040	Both
LAEL147_000784800 6-phosphogluconate dehydrogenase, decarboxyla	—	OG6 Tb927.10.2890 ↔ Tb927.9.12110 OG7 Tb927.10.2890 ↔ Tb927.9.12110	Both
LAEL147_000448800 kynureninase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.9.2010 OG7 Tb927.10.2890 ↔ Tb927.9.2010	Both
LAEL147_000229400 aspartate carbamoyltransferase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.5.3820 OG7 Tb927.10.2890 ↔ Tb927.5.3820	Both
LAEL147_000264900 citrate synthase, putative	—	OG6 Tb927.10.13430 ↔ Tb927.10.2890 OG7 Tb927.10.13430 ↔ Tb927.10.2890	Both
LAEL147_000433800 aspartate--ammonia ligase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.7.1110 OG7 Tb927.10.2890 ↔ Tb927.7.1110	Both
LAEL147_000376600 ⚠ fumarate hydratase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
LAEL147_000536200 ⚠ fumarate hydratase, putative	—	OG6 Tb927.10.2890 ↔ Tb927.11.5050 OG6 Tb927.10.2890 ↔ Tb927.3.4500 OG7 Tb927.10.2890 ↔ Tb927.11.5050 OG7 Tb927.10.2890 ↔ Tb927.3.4500	Both
LAEL147_000653300 nucleoside diphosphate kinase b	—	OG6 Tb927.10.2890 ↔ Tb927.11.16130 OG7 Tb927.10.2890 ↔ Tb927.11.16130	Both
LAEL147_000538200 C-8 sterol isomerase-like protein	—	OG6 Tb927.10.2890 ↔ Tb927.3.4650 OG7 Tb927.10.2890 ↔ Tb927.3.4650	Both
LAEL147_000133800 isocitrate dehydrogenase [NADP], mitochondria	—	OG6 Tb927.10.2890 ↔ Tb927.11.900 OG7 Tb927.10.2890 ↔ Tb927.11.900	Both
LAEL147_000809100 ⚠ elongation factor 2	—	OG6 Tb927.10.2890 ↔ Tb927.10.4560 OG7 Tb927.10.2890 ↔ Tb927.10.4560	Both
LAEL147_000381400 ⚠ malic enzyme, putative	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
LAEL147_000809200 ⚠ small GTP-binding protein domain containing p	—	OG6 Tb927.10.2890 ↔ Tb927.10.4560 OG7 Tb927.10.2890 ↔ Tb927.10.4560	Both